Aniline Violet
Brand names,
Aniline Violet
Analogs
Aniline Violet
Brand Names Mixture
Aniline Violet
Chemical_Formula
C25H30N3+
Aniline Violet
RX_link
No information avaliable
Aniline Violet
fda sheet
Aniline Violet
msds (material safety sheet)
Aniline Violet
Synthesis Reference
No information avaliable
Aniline Violet
Molecular Weight
372.526 g/mol
Aniline Violet
Melting Point
215 oC
Aniline Violet
H2O Solubility
4 mg/mL
Aniline Violet
State
Solid
Aniline Violet
LogP
3.18
Aniline Violet
Dosage Forms
Liquid; Tincture
Aniline Violet
Indication
For the treatment of bacterial and fungal infections inside the mouth (thrush) and skin, also for the prevention of transmission of Chagas' disease (as a blood additive).
Aniline Violet
Pharmacology
Gentian violet is a mutagen, a mitotic poison, and a clastogen. Gentian violet has been used in medicine for almost 100 years: as an antiseptic for external use, as a topical antibiotic, as a topical antifungal agent, as an antihelminthic agent by oral administration, and more recently, as a blood additive to prevent transmission of Chagas' disease. It is thought to work by binding to the DNA of target organisms and causing disruption, mutation or inhibition of DNA replication.
Aniline Violet
Absorption
No information avaliable
Aniline Violet
side effects and Toxicity
LD50=420 mg/kg (rat, oral). Oral administration can cause gastrointestinal irritation, and intravenous injection can cause depression in the white blood cell count.
Aniline Violet
Patient Information
Aniline Violet
Organisms Affected
Yeast and other fungi, bacteria and protozoans