Vermicid
Brand names,
Vermicid
Analogs
Vermicid
Brand Names Mixture
Vermicid
Chemical_Formula
C25H30N3+
Vermicid
RX_link
No information avaliable
Vermicid
fda sheet
Vermicid
msds (material safety sheet)
Vermicid
Synthesis Reference
No information avaliable
Vermicid
Molecular Weight
372.526 g/mol
Vermicid
Melting Point
215 oC
Vermicid
H2O Solubility
4 mg/mL
Vermicid
State
Solid
Vermicid
LogP
3.18
Vermicid
Dosage Forms
Liquid; Tincture
Vermicid
Indication
For the treatment of bacterial and fungal infections inside the mouth (thrush) and skin, also for the prevention of transmission of Chagas' disease (as a blood additive).
Vermicid
Pharmacology
Gentian violet is a mutagen, a mitotic poison, and a clastogen. Gentian violet has been used in medicine for almost 100 years: as an antiseptic for external use, as a topical antibiotic, as a topical antifungal agent, as an antihelminthic agent by oral administration, and more recently, as a blood additive to prevent transmission of Chagas' disease. It is thought to work by binding to the DNA of target organisms and causing disruption, mutation or inhibition of DNA replication.
Vermicid
Absorption
No information avaliable
Vermicid
side effects and Toxicity
LD50=420 mg/kg (rat, oral). Oral administration can cause gastrointestinal irritation, and intravenous injection can cause depression in the white blood cell count.
Vermicid
Patient Information
Vermicid
Organisms Affected
Yeast and other fungi, bacteria and protozoans