Genticid
Brand names,
Genticid
Analogs
Genticid
Brand Names Mixture
Genticid
Chemical_Formula
C25H30N3+
Genticid
RX_link
No information avaliable
Genticid
fda sheet
Genticid
msds (material safety sheet)
Genticid
Synthesis Reference
No information avaliable
Genticid
Molecular Weight
372.526 g/mol
Genticid
Melting Point
215 oC
Genticid
H2O Solubility
4 mg/mL
Genticid
State
Solid
Genticid
LogP
3.18
Genticid
Dosage Forms
Liquid; Tincture
Genticid
Indication
For the treatment of bacterial and fungal infections inside the mouth (thrush) and skin, also for the prevention of transmission of Chagas' disease (as a blood additive).
Genticid
Pharmacology
Gentian violet is a mutagen, a mitotic poison, and a clastogen. Gentian violet has been used in medicine for almost 100 years: as an antiseptic for external use, as a topical antibiotic, as a topical antifungal agent, as an antihelminthic agent by oral administration, and more recently, as a blood additive to prevent transmission of Chagas' disease. It is thought to work by binding to the DNA of target organisms and causing disruption, mutation or inhibition of DNA replication.
Genticid
Absorption
No information avaliable
Genticid
side effects and Toxicity
LD50=420 mg/kg (rat, oral). Oral administration can cause gastrointestinal irritation, and intravenous injection can cause depression in the white blood cell count.
Genticid
Patient Information
Genticid
Organisms Affected
Yeast and other fungi, bacteria and protozoans