C.I. Basic Violet 3
Brand names,
C.I. Basic Violet 3
Analogs
C.I. Basic Violet 3
Brand Names Mixture
C.I. Basic Violet 3
Chemical_Formula
C25H30N3+
C.I. Basic Violet 3
RX_link
No information avaliable
C.I. Basic Violet 3
fda sheet
C.I. Basic Violet 3
msds (material safety sheet)
C.I. Basic Violet 3
Synthesis Reference
No information avaliable
C.I. Basic Violet 3
Molecular Weight
372.526 g/mol
C.I. Basic Violet 3
Melting Point
215 oC
C.I. Basic Violet 3
H2O Solubility
4 mg/mL
C.I. Basic Violet 3
State
Solid
C.I. Basic Violet 3
LogP
3.18
C.I. Basic Violet 3
Dosage Forms
Liquid; Tincture
C.I. Basic Violet 3
Indication
For the treatment of bacterial and fungal infections inside the mouth (thrush) and skin, also for the prevention of transmission of Chagas' disease (as a blood additive).
C.I. Basic Violet 3
Pharmacology
Gentian violet is a mutagen, a mitotic poison, and a clastogen. Gentian violet has been used in medicine for almost 100 years: as an antiseptic for external use, as a topical antibiotic, as a topical antifungal agent, as an antihelminthic agent by oral administration, and more recently, as a blood additive to prevent transmission of Chagas' disease. It is thought to work by binding to the DNA of target organisms and causing disruption, mutation or inhibition of DNA replication.
C.I. Basic Violet 3
Absorption
No information avaliable
C.I. Basic Violet 3
side effects and Toxicity
LD50=420 mg/kg (rat, oral). Oral administration can cause gastrointestinal irritation, and intravenous injection can cause depression in the white blood cell count.
C.I. Basic Violet 3
Patient Information
C.I. Basic Violet 3
Organisms Affected
Yeast and other fungi, bacteria and protozoans