Methylrosaniline chloride
Brand names,
Methylrosaniline chloride
Analogs
Methylrosaniline chloride
Brand Names Mixture
Methylrosaniline chloride
Chemical_Formula
C25H30N3+
Methylrosaniline chloride
RX_link
No information avaliable
Methylrosaniline chloride
fda sheet
Methylrosaniline chloride
msds (material safety sheet)
Methylrosaniline chloride
Synthesis Reference
No information avaliable
Methylrosaniline chloride
Molecular Weight
372.526 g/mol
Methylrosaniline chloride
Melting Point
215 oC
Methylrosaniline chloride
H2O Solubility
4 mg/mL
Methylrosaniline chloride
State
Solid
Methylrosaniline chloride
LogP
3.18
Methylrosaniline chloride
Dosage Forms
Liquid; Tincture
Methylrosaniline chloride
Indication
For the treatment of bacterial and fungal infections inside the mouth (thrush) and skin, also for the prevention of transmission of Chagas' disease (as a blood additive).
Methylrosaniline chloride
Pharmacology
Gentian violet is a mutagen, a mitotic poison, and a clastogen. Gentian violet has been used in medicine for almost 100 years: as an antiseptic for external use, as a topical antibiotic, as a topical antifungal agent, as an antihelminthic agent by oral administration, and more recently, as a blood additive to prevent transmission of Chagas' disease. It is thought to work by binding to the DNA of target organisms and causing disruption, mutation or inhibition of DNA replication.
Methylrosaniline chloride
Absorption
No information avaliable
Methylrosaniline chloride
side effects and Toxicity
LD50=420 mg/kg (rat, oral). Oral administration can cause gastrointestinal irritation, and intravenous injection can cause depression in the white blood cell count.
Methylrosaniline chloride
Patient Information
Methylrosaniline chloride
Organisms Affected
Yeast and other fungi, bacteria and protozoans