Brilliant Violet 5B
Brand names,
Brilliant Violet 5B
Analogs
Brilliant Violet 5B
Brand Names Mixture
Brilliant Violet 5B
Chemical_Formula
C25H30N3+
Brilliant Violet 5B
RX_link
No information avaliable
Brilliant Violet 5B
fda sheet
Brilliant Violet 5B
msds (material safety sheet)
Brilliant Violet 5B
Synthesis Reference
No information avaliable
Brilliant Violet 5B
Molecular Weight
372.526 g/mol
Brilliant Violet 5B
Melting Point
215 oC
Brilliant Violet 5B
H2O Solubility
4 mg/mL
Brilliant Violet 5B
State
Solid
Brilliant Violet 5B
LogP
3.18
Brilliant Violet 5B
Dosage Forms
Liquid; Tincture
Brilliant Violet 5B
Indication
For the treatment of bacterial and fungal infections inside the mouth (thrush) and skin, also for the prevention of transmission of Chagas' disease (as a blood additive).
Brilliant Violet 5B
Pharmacology
Gentian violet is a mutagen, a mitotic poison, and a clastogen. Gentian violet has been used in medicine for almost 100 years: as an antiseptic for external use, as a topical antibiotic, as a topical antifungal agent, as an antihelminthic agent by oral administration, and more recently, as a blood additive to prevent transmission of Chagas' disease. It is thought to work by binding to the DNA of target organisms and causing disruption, mutation or inhibition of DNA replication.
Brilliant Violet 5B
Absorption
No information avaliable
Brilliant Violet 5B
side effects and Toxicity
LD50=420 mg/kg (rat, oral). Oral administration can cause gastrointestinal irritation, and intravenous injection can cause depression in the white blood cell count.
Brilliant Violet 5B
Patient Information
Brilliant Violet 5B
Organisms Affected
Yeast and other fungi, bacteria and protozoans