Oxycolor
Brand names,
Oxycolor
Analogs
Oxycolor
Brand Names Mixture
Oxycolor
Chemical_Formula
C25H30N3+
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RX_link
No information avaliable
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fda sheet
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msds (material safety sheet)
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Synthesis Reference
No information avaliable
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Molecular Weight
372.526 g/mol
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Melting Point
215 oC
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H2O Solubility
4 mg/mL
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State
Solid
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LogP
3.18
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Dosage Forms
Liquid; Tincture
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Indication
For the treatment of bacterial and fungal infections inside the mouth (thrush) and skin, also for the prevention of transmission of Chagas' disease (as a blood additive).
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Pharmacology
Gentian violet is a mutagen, a mitotic poison, and a clastogen. Gentian violet has been used in medicine for almost 100 years: as an antiseptic for external use, as a topical antibiotic, as a topical antifungal agent, as an antihelminthic agent by oral administration, and more recently, as a blood additive to prevent transmission of Chagas' disease. It is thought to work by binding to the DNA of target organisms and causing disruption, mutation or inhibition of DNA replication.
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Absorption
No information avaliable
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side effects and Toxicity
LD50=420 mg/kg (rat, oral). Oral administration can cause gastrointestinal irritation, and intravenous injection can cause depression in the white blood cell count.
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Patient Information
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Organisms Affected
Yeast and other fungi, bacteria and protozoans