Badil
Brand names,
Badil
Analogs
Badil
Brand Names Mixture
Badil
Chemical_Formula
C25H30N3+
Badil
RX_link
No information avaliable
Badil
fda sheet
Badil
msds (material safety sheet)
Badil
Synthesis Reference
No information avaliable
Badil
Molecular Weight
372.526 g/mol
Badil
Melting Point
215 oC
Badil
H2O Solubility
4 mg/mL
Badil
State
Solid
Badil
LogP
3.18
Badil
Dosage Forms
Liquid; Tincture
Badil
Indication
For the treatment of bacterial and fungal infections inside the mouth (thrush) and skin, also for the prevention of transmission of Chagas' disease (as a blood additive).
Badil
Pharmacology
Gentian violet is a mutagen, a mitotic poison, and a clastogen. Gentian violet has been used in medicine for almost 100 years: as an antiseptic for external use, as a topical antibiotic, as a topical antifungal agent, as an antihelminthic agent by oral administration, and more recently, as a blood additive to prevent transmission of Chagas' disease. It is thought to work by binding to the DNA of target organisms and causing disruption, mutation or inhibition of DNA replication.
Badil
Absorption
No information avaliable
Badil
side effects and Toxicity
LD50=420 mg/kg (rat, oral). Oral administration can cause gastrointestinal irritation, and intravenous injection can cause depression in the white blood cell count.
Badil
Patient Information
Badil
Organisms Affected
Yeast and other fungi, bacteria and protozoans