Bismuth Violet
Brand names,
Bismuth Violet
Analogs
Bismuth Violet
Brand Names Mixture
Bismuth Violet
Chemical_Formula
C25H30N3+
Bismuth Violet
RX_link
No information avaliable
Bismuth Violet
fda sheet
Bismuth Violet
msds (material safety sheet)
Bismuth Violet
Synthesis Reference
No information avaliable
Bismuth Violet
Molecular Weight
372.526 g/mol
Bismuth Violet
Melting Point
215 oC
Bismuth Violet
H2O Solubility
4 mg/mL
Bismuth Violet
State
Solid
Bismuth Violet
LogP
3.18
Bismuth Violet
Dosage Forms
Liquid; Tincture
Bismuth Violet
Indication
For the treatment of bacterial and fungal infections inside the mouth (thrush) and skin, also for the prevention of transmission of Chagas' disease (as a blood additive).
Bismuth Violet
Pharmacology
Gentian violet is a mutagen, a mitotic poison, and a clastogen. Gentian violet has been used in medicine for almost 100 years: as an antiseptic for external use, as a topical antibiotic, as a topical antifungal agent, as an antihelminthic agent by oral administration, and more recently, as a blood additive to prevent transmission of Chagas' disease. It is thought to work by binding to the DNA of target organisms and causing disruption, mutation or inhibition of DNA replication.
Bismuth Violet
Absorption
No information avaliable
Bismuth Violet
side effects and Toxicity
LD50=420 mg/kg (rat, oral). Oral administration can cause gastrointestinal irritation, and intravenous injection can cause depression in the white blood cell count.
Bismuth Violet
Patient Information
Bismuth Violet
Organisms Affected
Yeast and other fungi, bacteria and protozoans