Violet 5BO
Brand names,
Violet 5BO
Analogs
Violet 5BO
Brand Names Mixture
Violet 5BO
Chemical_Formula
C25H30N3+
Violet 5BO
RX_link
No information avaliable
Violet 5BO
fda sheet
Violet 5BO
msds (material safety sheet)
Violet 5BO
Synthesis Reference
No information avaliable
Violet 5BO
Molecular Weight
372.526 g/mol
Violet 5BO
Melting Point
215 oC
Violet 5BO
H2O Solubility
4 mg/mL
Violet 5BO
State
Solid
Violet 5BO
LogP
3.18
Violet 5BO
Dosage Forms
Liquid; Tincture
Violet 5BO
Indication
For the treatment of bacterial and fungal infections inside the mouth (thrush) and skin, also for the prevention of transmission of Chagas' disease (as a blood additive).
Violet 5BO
Pharmacology
Gentian violet is a mutagen, a mitotic poison, and a clastogen. Gentian violet has been used in medicine for almost 100 years: as an antiseptic for external use, as a topical antibiotic, as a topical antifungal agent, as an antihelminthic agent by oral administration, and more recently, as a blood additive to prevent transmission of Chagas' disease. It is thought to work by binding to the DNA of target organisms and causing disruption, mutation or inhibition of DNA replication.
Violet 5BO
Absorption
No information avaliable
Violet 5BO
side effects and Toxicity
LD50=420 mg/kg (rat, oral). Oral administration can cause gastrointestinal irritation, and intravenous injection can cause depression in the white blood cell count.
Violet 5BO
Patient Information
Violet 5BO
Organisms Affected
Yeast and other fungi, bacteria and protozoans