Aniline Violet pyoktanine
Brand names,
Aniline Violet pyoktanine
Analogs
Aniline Violet pyoktanine
Brand Names Mixture
Aniline Violet pyoktanine
Chemical_Formula
C25H30N3+
Aniline Violet pyoktanine
RX_link
No information avaliable
Aniline Violet pyoktanine
fda sheet
Aniline Violet pyoktanine
msds (material safety sheet)
Aniline Violet pyoktanine
Synthesis Reference
No information avaliable
Aniline Violet pyoktanine
Molecular Weight
372.526 g/mol
Aniline Violet pyoktanine
Melting Point
215 oC
Aniline Violet pyoktanine
H2O Solubility
4 mg/mL
Aniline Violet pyoktanine
State
Solid
Aniline Violet pyoktanine
LogP
3.18
Aniline Violet pyoktanine
Dosage Forms
Liquid; Tincture
Aniline Violet pyoktanine
Indication
For the treatment of bacterial and fungal infections inside the mouth (thrush) and skin, also for the prevention of transmission of Chagas' disease (as a blood additive).
Aniline Violet pyoktanine
Pharmacology
Gentian violet is a mutagen, a mitotic poison, and a clastogen. Gentian violet has been used in medicine for almost 100 years: as an antiseptic for external use, as a topical antibiotic, as a topical antifungal agent, as an antihelminthic agent by oral administration, and more recently, as a blood additive to prevent transmission of Chagas' disease. It is thought to work by binding to the DNA of target organisms and causing disruption, mutation or inhibition of DNA replication.
Aniline Violet pyoktanine
Absorption
No information avaliable
Aniline Violet pyoktanine
side effects and Toxicity
LD50=420 mg/kg (rat, oral). Oral administration can cause gastrointestinal irritation, and intravenous injection can cause depression in the white blood cell count.
Aniline Violet pyoktanine
Patient Information
Aniline Violet pyoktanine
Organisms Affected
Yeast and other fungi, bacteria and protozoans