Methyl violet
Brand names,
Methyl violet
Analogs
Methyl violet
Brand Names Mixture
Methyl violet
Chemical_Formula
C25H30N3+
Methyl violet
RX_link
No information avaliable
Methyl violet
fda sheet
Methyl violet
msds (material safety sheet)
Methyl violet
Synthesis Reference
No information avaliable
Methyl violet
Molecular Weight
372.526 g/mol
Methyl violet
Melting Point
215 oC
Methyl violet
H2O Solubility
4 mg/mL
Methyl violet
State
Solid
Methyl violet
LogP
3.18
Methyl violet
Dosage Forms
Liquid; Tincture
Methyl violet
Indication
For the treatment of bacterial and fungal infections inside the mouth (thrush) and skin, also for the prevention of transmission of Chagas' disease (as a blood additive).
Methyl violet
Pharmacology
Gentian violet is a mutagen, a mitotic poison, and a clastogen. Gentian violet has been used in medicine for almost 100 years: as an antiseptic for external use, as a topical antibiotic, as a topical antifungal agent, as an antihelminthic agent by oral administration, and more recently, as a blood additive to prevent transmission of Chagas' disease. It is thought to work by binding to the DNA of target organisms and causing disruption, mutation or inhibition of DNA replication.
Methyl violet
Absorption
No information avaliable
Methyl violet
side effects and Toxicity
LD50=420 mg/kg (rat, oral). Oral administration can cause gastrointestinal irritation, and intravenous injection can cause depression in the white blood cell count.
Methyl violet
Patient Information
Methyl violet
Organisms Affected
Yeast and other fungi, bacteria and protozoans