Avermin
Brand names,
Avermin
Analogs
Avermin
Brand Names Mixture
Avermin
Chemical_Formula
C25H30N3+
Avermin
RX_link
No information avaliable
Avermin
fda sheet
Avermin
msds (material safety sheet)
Avermin
Synthesis Reference
No information avaliable
Avermin
Molecular Weight
372.526 g/mol
Avermin
Melting Point
215 oC
Avermin
H2O Solubility
4 mg/mL
Avermin
State
Solid
Avermin
LogP
3.18
Avermin
Dosage Forms
Liquid; Tincture
Avermin
Indication
For the treatment of bacterial and fungal infections inside the mouth (thrush) and skin, also for the prevention of transmission of Chagas' disease (as a blood additive).
Avermin
Pharmacology
Gentian violet is a mutagen, a mitotic poison, and a clastogen. Gentian violet has been used in medicine for almost 100 years: as an antiseptic for external use, as a topical antibiotic, as a topical antifungal agent, as an antihelminthic agent by oral administration, and more recently, as a blood additive to prevent transmission of Chagas' disease. It is thought to work by binding to the DNA of target organisms and causing disruption, mutation or inhibition of DNA replication.
Avermin
Absorption
No information avaliable
Avermin
side effects and Toxicity
LD50=420 mg/kg (rat, oral). Oral administration can cause gastrointestinal irritation, and intravenous injection can cause depression in the white blood cell count.
Avermin
Patient Information
Avermin
Organisms Affected
Yeast and other fungi, bacteria and protozoans