Calcozine Violet C
Brand names,
Calcozine Violet C
Analogs
Calcozine Violet C
Brand Names Mixture
Calcozine Violet C
Chemical_Formula
C25H30N3+
Calcozine Violet C
RX_link
No information avaliable
Calcozine Violet C
fda sheet
Calcozine Violet C
msds (material safety sheet)
Calcozine Violet C
Synthesis Reference
No information avaliable
Calcozine Violet C
Molecular Weight
372.526 g/mol
Calcozine Violet C
Melting Point
215 oC
Calcozine Violet C
H2O Solubility
4 mg/mL
Calcozine Violet C
State
Solid
Calcozine Violet C
LogP
3.18
Calcozine Violet C
Dosage Forms
Liquid; Tincture
Calcozine Violet C
Indication
For the treatment of bacterial and fungal infections inside the mouth (thrush) and skin, also for the prevention of transmission of Chagas' disease (as a blood additive).
Calcozine Violet C
Pharmacology
Gentian violet is a mutagen, a mitotic poison, and a clastogen. Gentian violet has been used in medicine for almost 100 years: as an antiseptic for external use, as a topical antibiotic, as a topical antifungal agent, as an antihelminthic agent by oral administration, and more recently, as a blood additive to prevent transmission of Chagas' disease. It is thought to work by binding to the DNA of target organisms and causing disruption, mutation or inhibition of DNA replication.
Calcozine Violet C
Absorption
No information avaliable
Calcozine Violet C
side effects and Toxicity
LD50=420 mg/kg (rat, oral). Oral administration can cause gastrointestinal irritation, and intravenous injection can cause depression in the white blood cell count.
Calcozine Violet C
Patient Information
Calcozine Violet C
Organisms Affected
Yeast and other fungi, bacteria and protozoans