methylrosanilinium chloride
Brand names,
methylrosanilinium chloride
Analogs
methylrosanilinium chloride
Brand Names Mixture
methylrosanilinium chloride
Chemical_Formula
C25H30N3+
methylrosanilinium chloride
RX_link
No information avaliable
methylrosanilinium chloride
fda sheet
methylrosanilinium chloride
msds (material safety sheet)
methylrosanilinium chloride
Synthesis Reference
No information avaliable
methylrosanilinium chloride
Molecular Weight
372.526 g/mol
methylrosanilinium chloride
Melting Point
215 oC
methylrosanilinium chloride
H2O Solubility
4 mg/mL
methylrosanilinium chloride
State
Solid
methylrosanilinium chloride
LogP
3.18
methylrosanilinium chloride
Dosage Forms
Liquid; Tincture
methylrosanilinium chloride
Indication
For the treatment of bacterial and fungal infections inside the mouth (thrush) and skin, also for the prevention of transmission of Chagas' disease (as a blood additive).
methylrosanilinium chloride
Pharmacology
Gentian violet is a mutagen, a mitotic poison, and a clastogen. Gentian violet has been used in medicine for almost 100 years: as an antiseptic for external use, as a topical antibiotic, as a topical antifungal agent, as an antihelminthic agent by oral administration, and more recently, as a blood additive to prevent transmission of Chagas' disease. It is thought to work by binding to the DNA of target organisms and causing disruption, mutation or inhibition of DNA replication.
methylrosanilinium chloride
Absorption
No information avaliable
methylrosanilinium chloride
side effects and Toxicity
LD50=420 mg/kg (rat, oral). Oral administration can cause gastrointestinal irritation, and intravenous injection can cause depression in the white blood cell count.
methylrosanilinium chloride
Patient Information
methylrosanilinium chloride
Organisms Affected
Yeast and other fungi, bacteria and protozoans