Oxiuran
Brand names,
Oxiuran
Analogs
Oxiuran
Brand Names Mixture
Oxiuran
Chemical_Formula
C25H30N3+
Oxiuran
RX_link
No information avaliable
Oxiuran
fda sheet
Oxiuran
msds (material safety sheet)
Oxiuran
Synthesis Reference
No information avaliable
Oxiuran
Molecular Weight
372.526 g/mol
Oxiuran
Melting Point
215 oC
Oxiuran
H2O Solubility
4 mg/mL
Oxiuran
State
Solid
Oxiuran
LogP
3.18
Oxiuran
Dosage Forms
Liquid; Tincture
Oxiuran
Indication
For the treatment of bacterial and fungal infections inside the mouth (thrush) and skin, also for the prevention of transmission of Chagas' disease (as a blood additive).
Oxiuran
Pharmacology
Gentian violet is a mutagen, a mitotic poison, and a clastogen. Gentian violet has been used in medicine for almost 100 years: as an antiseptic for external use, as a topical antibiotic, as a topical antifungal agent, as an antihelminthic agent by oral administration, and more recently, as a blood additive to prevent transmission of Chagas' disease. It is thought to work by binding to the DNA of target organisms and causing disruption, mutation or inhibition of DNA replication.
Oxiuran
Absorption
No information avaliable
Oxiuran
side effects and Toxicity
LD50=420 mg/kg (rat, oral). Oral administration can cause gastrointestinal irritation, and intravenous injection can cause depression in the white blood cell count.
Oxiuran
Patient Information
Oxiuran
Organisms Affected
Yeast and other fungi, bacteria and protozoans