Calcozine Violet 6BN
Brand names,
Calcozine Violet 6BN
Analogs
Calcozine Violet 6BN
Brand Names Mixture
Calcozine Violet 6BN
Chemical_Formula
C25H30N3+
Calcozine Violet 6BN
RX_link
No information avaliable
Calcozine Violet 6BN
fda sheet
Calcozine Violet 6BN
msds (material safety sheet)
Calcozine Violet 6BN
Synthesis Reference
No information avaliable
Calcozine Violet 6BN
Molecular Weight
372.526 g/mol
Calcozine Violet 6BN
Melting Point
215 oC
Calcozine Violet 6BN
H2O Solubility
4 mg/mL
Calcozine Violet 6BN
State
Solid
Calcozine Violet 6BN
LogP
3.18
Calcozine Violet 6BN
Dosage Forms
Liquid; Tincture
Calcozine Violet 6BN
Indication
For the treatment of bacterial and fungal infections inside the mouth (thrush) and skin, also for the prevention of transmission of Chagas' disease (as a blood additive).
Calcozine Violet 6BN
Pharmacology
Gentian violet is a mutagen, a mitotic poison, and a clastogen. Gentian violet has been used in medicine for almost 100 years: as an antiseptic for external use, as a topical antibiotic, as a topical antifungal agent, as an antihelminthic agent by oral administration, and more recently, as a blood additive to prevent transmission of Chagas' disease. It is thought to work by binding to the DNA of target organisms and causing disruption, mutation or inhibition of DNA replication.
Calcozine Violet 6BN
Absorption
No information avaliable
Calcozine Violet 6BN
side effects and Toxicity
LD50=420 mg/kg (rat, oral). Oral administration can cause gastrointestinal irritation, and intravenous injection can cause depression in the white blood cell count.
Calcozine Violet 6BN
Patient Information
Calcozine Violet 6BN
Organisms Affected
Yeast and other fungi, bacteria and protozoans