Viocid
Brand names,
Viocid
Analogs
Viocid
Brand Names Mixture
Viocid
Chemical_Formula
C25H30N3+
Viocid
RX_link
No information avaliable
Viocid
fda sheet
Viocid
msds (material safety sheet)
Viocid
Synthesis Reference
No information avaliable
Viocid
Molecular Weight
372.526 g/mol
Viocid
Melting Point
215 oC
Viocid
H2O Solubility
4 mg/mL
Viocid
State
Solid
Viocid
LogP
3.18
Viocid
Dosage Forms
Liquid; Tincture
Viocid
Indication
For the treatment of bacterial and fungal infections inside the mouth (thrush) and skin, also for the prevention of transmission of Chagas' disease (as a blood additive).
Viocid
Pharmacology
Gentian violet is a mutagen, a mitotic poison, and a clastogen. Gentian violet has been used in medicine for almost 100 years: as an antiseptic for external use, as a topical antibiotic, as a topical antifungal agent, as an antihelminthic agent by oral administration, and more recently, as a blood additive to prevent transmission of Chagas' disease. It is thought to work by binding to the DNA of target organisms and causing disruption, mutation or inhibition of DNA replication.
Viocid
Absorption
No information avaliable
Viocid
side effects and Toxicity
LD50=420 mg/kg (rat, oral). Oral administration can cause gastrointestinal irritation, and intravenous injection can cause depression in the white blood cell count.
Viocid
Patient Information
Viocid
Organisms Affected
Yeast and other fungi, bacteria and protozoans