Phenformin HCl
Phenformin HCl Brand names, Phenformin HCl Analogs
- Azucaps
- Beta-Pebg
- Beta-Phenethybiguanide
- Beta-Phenethylbiguanide
- Cronoformin
- D Bretard
- DBI
- DB Comb
- DB-Retard
- DBI Monohydrochloride
- Debeone
- Debinyl
- Diabis
- Dibein
- Dibiraf
- Dibotin
- Dipar
- Feguanide
- Fenfoduron
- Fenformin
- Fenformina
- Fenformina [Inn-Spanish]
- Fenormin
- Glukopostin
- Glyphen
- Insoral
- Lentobetic
- Meltrol
- Meltrol-50
- N-Phenethylbiguanide Hydrochloride
- Normoglucina
- Pedg
- Phenethylbiguanide Hydrochloride
- Phenethyldiguanide
- Phenformin HCl
- Phenformin Hydrochloride
- Phenformine
- Phenformine HCl
- Phenformine [Inn-French]
- Phenforminum [Inn-Latin]
- Phenformix
- Phenoformine Hydrochloride
- Phenylethylbiguanide
- Retardo
Phenformin HCl Brand Names Mixture
- No information avaliable
Phenformin HCl Chemical_Formula
C10H15N5
Phenformin HCl RX_link
No information avaliable
Phenformin HCl fda sheet
Phenformin HCl msds (material safety sheet)
Phenformin HCl Synthesis Reference
Shapiro, Freedman, U.S. pats. 2,961,377, 3,057,780 (1960, 1962 both to U.S.V.)
Phenformin HCl Molecular Weight
205.26 g/mol
Phenformin HCl Melting Point
175-178 oC
Phenformin HCl H2O Solubility
210 mg/mL
Phenformin HCl State
Solid
Phenformin HCl LogP
0.759
Phenformin HCl Dosage Forms
No information avaliable
Phenformin HCl Indication
For the reatment of type II diabetes mellitus.
Phenformin HCl Pharmacology
Used to treat diabetes, phenformin is a biguanide (contains 2 guanidino groups) hypoglycemic agent with actions and uses similar to those of metformin (Glucophage). Both drugs work by (1) decreasing the absorption of glucose by the intestines, (2) decreasing the production of glucose in the liver, and by (3) increasing the body's ability to use insulin more effectively. More specifically, phenformin improves glycemic control by improving insulin sensitivity. Phenformin is generally considered to be associated with an unacceptably high incidence of actic acidosis. In general biguanides should be used only in stable type II diabetics who are free of liver, kidney and cardiovascular problems and who cannot be controlled with diet.
Phenformin HCl Absorption
No information avaliable
Phenformin HCl side effects and Toxicity
No information avaliable
Phenformin HCl Patient Information
No information avaliable
Phenformin HCl Organisms Affected
Humans and other mammals
