Feguanide
Feguanide Brand names, Feguanide Analogs
- Azucaps
- Beta-Pebg
- Beta-Phenethybiguanide
- Beta-Phenethylbiguanide
- Cronoformin
- D Bretard
- DBI
- DB Comb
- DB-Retard
- DBI Monohydrochloride
- Debeone
- Debinyl
- Diabis
- Dibein
- Dibiraf
- Dibotin
- Dipar
- Feguanide
- Fenfoduron
- Fenformin
- Fenformina
- Fenformina [Inn-Spanish]
- Fenormin
- Glukopostin
- Glyphen
- Insoral
- Lentobetic
- Meltrol
- Meltrol-50
- N-Phenethylbiguanide Hydrochloride
- Normoglucina
- Pedg
- Phenethylbiguanide Hydrochloride
- Phenethyldiguanide
- Phenformin HCl
- Phenformin Hydrochloride
- Phenformine
- Phenformine HCl
- Phenformine [Inn-French]
- Phenforminum [Inn-Latin]
- Phenformix
- Phenoformine Hydrochloride
- Phenylethylbiguanide
- Retardo
Feguanide Brand Names Mixture
- No information avaliable
Feguanide Chemical_Formula
C10H15N5
Feguanide RX_link
No information avaliable
Feguanide fda sheet
Feguanide msds (material safety sheet)
Feguanide Synthesis Reference
Shapiro, Freedman, U.S. pats. 2,961,377, 3,057,780 (1960, 1962 both to U.S.V.)
Feguanide Molecular Weight
205.26 g/mol
Feguanide Melting Point
175-178 oC
Feguanide H2O Solubility
210 mg/mL
Feguanide State
Solid
Feguanide LogP
0.759
Feguanide Dosage Forms
No information avaliable
Feguanide Indication
For the reatment of type II diabetes mellitus.
Feguanide Pharmacology
Used to treat diabetes, phenformin is a biguanide (contains 2 guanidino groups) hypoglycemic agent with actions and uses similar to those of metformin (Glucophage). Both drugs work by (1) decreasing the absorption of glucose by the intestines, (2) decreasing the production of glucose in the liver, and by (3) increasing the body's ability to use insulin more effectively. More specifically, phenformin improves glycemic control by improving insulin sensitivity. Phenformin is generally considered to be associated with an unacceptably high incidence of actic acidosis. In general biguanides should be used only in stable type II diabetics who are free of liver, kidney and cardiovascular problems and who cannot be controlled with diet.
Feguanide Absorption
No information avaliable
Feguanide side effects and Toxicity
No information avaliable
Feguanide Patient Information
No information avaliable
Feguanide Organisms Affected
Humans and other mammals
