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Feguanide Brand names, Feguanide Analogs

Feguanide Brand Names Mixture

  • No information avaliable

Feguanide Chemical_Formula


Feguanide RX_link

No information avaliable

Feguanide fda sheet

Feguanide msds (material safety sheet)

Feguanide Synthesis Reference

Shapiro, Freedman, U.S. pats. 2,961,377, 3,057,780 (1960, 1962 both to U.S.V.)

Feguanide Molecular Weight

205.26 g/mol

Feguanide Melting Point

175-178 oC

Feguanide H2O Solubility

210 mg/mL

Feguanide State


Feguanide LogP


Feguanide Dosage Forms

No information avaliable

Feguanide Indication

For the reatment of type II diabetes mellitus.

Feguanide Pharmacology

Used to treat diabetes, phenformin is a biguanide (contains 2 guanidino groups) hypoglycemic agent with actions and uses similar to those of metformin (Glucophage). Both drugs work by (1) decreasing the absorption of glucose by the intestines, (2) decreasing the production of glucose in the liver, and by (3) increasing the body's ability to use insulin more effectively. More specifically, phenformin improves glycemic control by improving insulin sensitivity. Phenformin is generally considered to be associated with an unacceptably high incidence of actic acidosis. In general biguanides should be used only in stable type II diabetics who are free of liver, kidney and cardiovascular problems and who cannot be controlled with diet.

Feguanide Absorption

No information avaliable

Feguanide side effects and Toxicity

No information avaliable

Feguanide Patient Information

No information avaliable

Feguanide Organisms Affected

Humans and other mammals