Phenformin Hydrochloride
Phenformin Hydrochloride Brand names, Phenformin Hydrochloride Analogs
- Azucaps
- Beta-Pebg
- Beta-Phenethybiguanide
- Beta-Phenethylbiguanide
- Cronoformin
- D Bretard
- DBI
- DB Comb
- DB-Retard
- DBI Monohydrochloride
- Debeone
- Debinyl
- Diabis
- Dibein
- Dibiraf
- Dibotin
- Dipar
- Feguanide
- Fenfoduron
- Fenformin
- Fenformina
- Fenformina [Inn-Spanish]
- Fenormin
- Glukopostin
- Glyphen
- Insoral
- Lentobetic
- Meltrol
- Meltrol-50
- N-Phenethylbiguanide Hydrochloride
- Normoglucina
- Pedg
- Phenethylbiguanide Hydrochloride
- Phenethyldiguanide
- Phenformin HCl
- Phenformin Hydrochloride
- Phenformine
- Phenformine HCl
- Phenformine [Inn-French]
- Phenforminum [Inn-Latin]
- Phenformix
- Phenoformine Hydrochloride
- Phenylethylbiguanide
- Retardo
Phenformin Hydrochloride Brand Names Mixture
- No information avaliable
Phenformin Hydrochloride Chemical_Formula
C10H15N5
Phenformin Hydrochloride RX_link
No information avaliable
Phenformin Hydrochloride fda sheet
Phenformin Hydrochloride msds (material safety sheet)
Phenformin Hydrochloride Synthesis Reference
Shapiro, Freedman, U.S. pats. 2,961,377, 3,057,780 (1960, 1962 both to U.S.V.)
Phenformin Hydrochloride Molecular Weight
205.26 g/mol
Phenformin Hydrochloride Melting Point
175-178 oC
Phenformin Hydrochloride H2O Solubility
210 mg/mL
Phenformin Hydrochloride State
Solid
Phenformin Hydrochloride LogP
0.759
Phenformin Hydrochloride Dosage Forms
No information avaliable
Phenformin Hydrochloride Indication
For the reatment of type II diabetes mellitus.
Phenformin Hydrochloride Pharmacology
Used to treat diabetes, phenformin is a biguanide (contains 2 guanidino groups) hypoglycemic agent with actions and uses similar to those of metformin (Glucophage). Both drugs work by (1) decreasing the absorption of glucose by the intestines, (2) decreasing the production of glucose in the liver, and by (3) increasing the body's ability to use insulin more effectively. More specifically, phenformin improves glycemic control by improving insulin sensitivity. Phenformin is generally considered to be associated with an unacceptably high incidence of actic acidosis. In general biguanides should be used only in stable type II diabetics who are free of liver, kidney and cardiovascular problems and who cannot be controlled with diet.
Phenformin Hydrochloride Absorption
No information avaliable
Phenformin Hydrochloride side effects and Toxicity
No information avaliable
Phenformin Hydrochloride Patient Information
No information avaliable
Phenformin Hydrochloride Organisms Affected
Humans and other mammals
