N-Phenethylbiguanide Hydrochloride
N-Phenethylbiguanide Hydrochloride Brand names, N-Phenethylbiguanide Hydrochloride Analogs
- Azucaps
- Beta-Pebg
- Beta-Phenethybiguanide
- Beta-Phenethylbiguanide
- Cronoformin
- D Bretard
- DBI
- DB Comb
- DB-Retard
- DBI Monohydrochloride
- Debeone
- Debinyl
- Diabis
- Dibein
- Dibiraf
- Dibotin
- Dipar
- Feguanide
- Fenfoduron
- Fenformin
- Fenformina
- Fenformina [Inn-Spanish]
- Fenormin
- Glukopostin
- Glyphen
- Insoral
- Lentobetic
- Meltrol
- Meltrol-50
- N-Phenethylbiguanide Hydrochloride
- Normoglucina
- Pedg
- Phenethylbiguanide Hydrochloride
- Phenethyldiguanide
- Phenformin HCl
- Phenformin Hydrochloride
- Phenformine
- Phenformine HCl
- Phenformine [Inn-French]
- Phenforminum [Inn-Latin]
- Phenformix
- Phenoformine Hydrochloride
- Phenylethylbiguanide
- Retardo
N-Phenethylbiguanide Hydrochloride Brand Names Mixture
- No information avaliable
N-Phenethylbiguanide Hydrochloride Chemical_Formula
C10H15N5
N-Phenethylbiguanide Hydrochloride RX_link
No information avaliable
N-Phenethylbiguanide Hydrochloride fda sheet
N-Phenethylbiguanide Hydrochloride msds (material safety sheet)
N-Phenethylbiguanide Hydrochloride Synthesis Reference
Shapiro, Freedman, U.S. pats. 2,961,377, 3,057,780 (1960, 1962 both to U.S.V.)
N-Phenethylbiguanide Hydrochloride Molecular Weight
205.26 g/mol
N-Phenethylbiguanide Hydrochloride Melting Point
175-178 oC
N-Phenethylbiguanide Hydrochloride H2O Solubility
210 mg/mL
N-Phenethylbiguanide Hydrochloride State
Solid
N-Phenethylbiguanide Hydrochloride LogP
0.759
N-Phenethylbiguanide Hydrochloride Dosage Forms
No information avaliable
N-Phenethylbiguanide Hydrochloride Indication
For the reatment of type II diabetes mellitus.
N-Phenethylbiguanide Hydrochloride Pharmacology
Used to treat diabetes, phenformin is a biguanide (contains 2 guanidino groups) hypoglycemic agent with actions and uses similar to those of metformin (Glucophage). Both drugs work by (1) decreasing the absorption of glucose by the intestines, (2) decreasing the production of glucose in the liver, and by (3) increasing the body's ability to use insulin more effectively. More specifically, phenformin improves glycemic control by improving insulin sensitivity. Phenformin is generally considered to be associated with an unacceptably high incidence of actic acidosis. In general biguanides should be used only in stable type II diabetics who are free of liver, kidney and cardiovascular problems and who cannot be controlled with diet.
N-Phenethylbiguanide Hydrochloride Absorption
No information avaliable
N-Phenethylbiguanide Hydrochloride side effects and Toxicity
No information avaliable
N-Phenethylbiguanide Hydrochloride Patient Information
No information avaliable
N-Phenethylbiguanide Hydrochloride Organisms Affected
Humans and other mammals
