Dibotin
Dibotin Brand names, Dibotin Analogs
- Azucaps
- Beta-Pebg
- Beta-Phenethybiguanide
- Beta-Phenethylbiguanide
- Cronoformin
- D Bretard
- DBI
- DB Comb
- DB-Retard
- DBI Monohydrochloride
- Debeone
- Debinyl
- Diabis
- Dibein
- Dibiraf
- Dibotin
- Dipar
- Feguanide
- Fenfoduron
- Fenformin
- Fenformina
- Fenformina [Inn-Spanish]
- Fenormin
- Glukopostin
- Glyphen
- Insoral
- Lentobetic
- Meltrol
- Meltrol-50
- N-Phenethylbiguanide Hydrochloride
- Normoglucina
- Pedg
- Phenethylbiguanide Hydrochloride
- Phenethyldiguanide
- Phenformin HCl
- Phenformin Hydrochloride
- Phenformine
- Phenformine HCl
- Phenformine [Inn-French]
- Phenforminum [Inn-Latin]
- Phenformix
- Phenoformine Hydrochloride
- Phenylethylbiguanide
- Retardo
Dibotin Brand Names Mixture
- No information avaliable
Dibotin Chemical_Formula
C10H15N5
Dibotin RX_link
No information avaliable
Dibotin fda sheet
Dibotin msds (material safety sheet)
Dibotin Synthesis Reference
Shapiro, Freedman, U.S. pats. 2,961,377, 3,057,780 (1960, 1962 both to U.S.V.)
Dibotin Molecular Weight
205.26 g/mol
Dibotin Melting Point
175-178 oC
Dibotin H2O Solubility
210 mg/mL
Dibotin State
Solid
Dibotin LogP
0.759
Dibotin Dosage Forms
No information avaliable
Dibotin Indication
For the reatment of type II diabetes mellitus.
Dibotin Pharmacology
Used to treat diabetes, phenformin is a biguanide (contains 2 guanidino groups) hypoglycemic agent with actions and uses similar to those of metformin (Glucophage). Both drugs work by (1) decreasing the absorption of glucose by the intestines, (2) decreasing the production of glucose in the liver, and by (3) increasing the body's ability to use insulin more effectively. More specifically, phenformin improves glycemic control by improving insulin sensitivity. Phenformin is generally considered to be associated with an unacceptably high incidence of actic acidosis. In general biguanides should be used only in stable type II diabetics who are free of liver, kidney and cardiovascular problems and who cannot be controlled with diet.
Dibotin Absorption
No information avaliable
Dibotin side effects and Toxicity
No information avaliable
Dibotin Patient Information
No information avaliable
Dibotin Organisms Affected
Humans and other mammals
