Fenformin
Fenformin Brand names, Fenformin Analogs
- Azucaps
- Beta-Pebg
- Beta-Phenethybiguanide
- Beta-Phenethylbiguanide
- Cronoformin
- D Bretard
- DBI
- DB Comb
- DB-Retard
- DBI Monohydrochloride
- Debeone
- Debinyl
- Diabis
- Dibein
- Dibiraf
- Dibotin
- Dipar
- Feguanide
- Fenfoduron
- Fenformin
- Fenformina
- Fenformina [Inn-Spanish]
- Fenormin
- Glukopostin
- Glyphen
- Insoral
- Lentobetic
- Meltrol
- Meltrol-50
- N-Phenethylbiguanide Hydrochloride
- Normoglucina
- Pedg
- Phenethylbiguanide Hydrochloride
- Phenethyldiguanide
- Phenformin HCl
- Phenformin Hydrochloride
- Phenformine
- Phenformine HCl
- Phenformine [Inn-French]
- Phenforminum [Inn-Latin]
- Phenformix
- Phenoformine Hydrochloride
- Phenylethylbiguanide
- Retardo
Fenformin Brand Names Mixture
- No information avaliable
Fenformin Chemical_Formula
C10H15N5
Fenformin RX_link
No information avaliable
Fenformin fda sheet
Fenformin msds (material safety sheet)
Fenformin Synthesis Reference
Shapiro, Freedman, U.S. pats. 2,961,377, 3,057,780 (1960, 1962 both to U.S.V.)
Fenformin Molecular Weight
205.26 g/mol
Fenformin Melting Point
175-178 oC
Fenformin H2O Solubility
210 mg/mL
Fenformin State
Solid
Fenformin LogP
0.759
Fenformin Dosage Forms
No information avaliable
Fenformin Indication
For the reatment of type II diabetes mellitus.
Fenformin Pharmacology
Used to treat diabetes, phenformin is a biguanide (contains 2 guanidino groups) hypoglycemic agent with actions and uses similar to those of metformin (Glucophage). Both drugs work by (1) decreasing the absorption of glucose by the intestines, (2) decreasing the production of glucose in the liver, and by (3) increasing the body's ability to use insulin more effectively. More specifically, phenformin improves glycemic control by improving insulin sensitivity. Phenformin is generally considered to be associated with an unacceptably high incidence of actic acidosis. In general biguanides should be used only in stable type II diabetics who are free of liver, kidney and cardiovascular problems and who cannot be controlled with diet.
Fenformin Absorption
No information avaliable
Fenformin side effects and Toxicity
No information avaliable
Fenformin Patient Information
No information avaliable
Fenformin Organisms Affected
Humans and other mammals
