Fenfoduron
Brand names,
Fenfoduron
Analogs
Fenfoduron
Brand Names Mixture
Fenfoduron
Chemical_Formula
C10H15N5
Fenfoduron
RX_link
No information avaliable
Fenfoduron
fda sheet
Fenfoduron
msds (material safety sheet)
Fenfoduron
Synthesis Reference
Shapiro, Freedman, U.S. pats. 2,961,377, 3,057,780 (1960, 1962 both to U.S.V.)
Fenfoduron
Molecular Weight
205.26 g/mol
Fenfoduron
Melting Point
175-178 oC
Fenfoduron
H2O Solubility
210 mg/mL
Fenfoduron
State
Solid
Fenfoduron
LogP
0.759
Fenfoduron
Dosage Forms
No information avaliable
Fenfoduron
Indication
For the reatment of type II diabetes mellitus.
Fenfoduron
Pharmacology
Used to treat diabetes, phenformin is a biguanide (contains 2 guanidino groups) hypoglycemic agent with actions and uses similar to those of metformin (Glucophage). Both drugs work by (1) decreasing the absorption of glucose by the intestines, (2) decreasing the production of glucose in the liver, and by (3) increasing the body's ability to use insulin more effectively. More specifically, phenformin improves glycemic control by improving insulin sensitivity. Phenformin is generally considered to be associated with an unacceptably high incidence of actic acidosis. In general biguanides should be used only in stable type II diabetics who are free of liver, kidney and cardiovascular problems and who cannot be controlled with diet.
Fenfoduron
Absorption
No information avaliable
Fenfoduron
side effects and Toxicity
No information avaliable
Fenfoduron
Patient Information
No information avaliable
Fenfoduron
Organisms Affected
Humans and other mammals