Phenylethylbiguanide
Phenylethylbiguanide Brand names, Phenylethylbiguanide Analogs
- Azucaps
- Beta-Pebg
- Beta-Phenethybiguanide
- Beta-Phenethylbiguanide
- Cronoformin
- D Bretard
- DBI
- DB Comb
- DB-Retard
- DBI Monohydrochloride
- Debeone
- Debinyl
- Diabis
- Dibein
- Dibiraf
- Dibotin
- Dipar
- Feguanide
- Fenfoduron
- Fenformin
- Fenformina
- Fenformina [Inn-Spanish]
- Fenormin
- Glukopostin
- Glyphen
- Insoral
- Lentobetic
- Meltrol
- Meltrol-50
- N-Phenethylbiguanide Hydrochloride
- Normoglucina
- Pedg
- Phenethylbiguanide Hydrochloride
- Phenethyldiguanide
- Phenformin HCl
- Phenformin Hydrochloride
- Phenformine
- Phenformine HCl
- Phenformine [Inn-French]
- Phenforminum [Inn-Latin]
- Phenformix
- Phenoformine Hydrochloride
- Phenylethylbiguanide
- Retardo
Phenylethylbiguanide Brand Names Mixture
- No information avaliable
Phenylethylbiguanide Chemical_Formula
C10H15N5
Phenylethylbiguanide RX_link
No information avaliable
Phenylethylbiguanide fda sheet
Phenylethylbiguanide msds (material safety sheet)
Phenylethylbiguanide Synthesis Reference
Shapiro, Freedman, U.S. pats. 2,961,377, 3,057,780 (1960, 1962 both to U.S.V.)
Phenylethylbiguanide Molecular Weight
205.26 g/mol
Phenylethylbiguanide Melting Point
175-178 oC
Phenylethylbiguanide H2O Solubility
210 mg/mL
Phenylethylbiguanide State
Solid
Phenylethylbiguanide LogP
0.759
Phenylethylbiguanide Dosage Forms
No information avaliable
Phenylethylbiguanide Indication
For the reatment of type II diabetes mellitus.
Phenylethylbiguanide Pharmacology
Used to treat diabetes, phenformin is a biguanide (contains 2 guanidino groups) hypoglycemic agent with actions and uses similar to those of metformin (Glucophage). Both drugs work by (1) decreasing the absorption of glucose by the intestines, (2) decreasing the production of glucose in the liver, and by (3) increasing the body's ability to use insulin more effectively. More specifically, phenformin improves glycemic control by improving insulin sensitivity. Phenformin is generally considered to be associated with an unacceptably high incidence of actic acidosis. In general biguanides should be used only in stable type II diabetics who are free of liver, kidney and cardiovascular problems and who cannot be controlled with diet.
Phenylethylbiguanide Absorption
No information avaliable
Phenylethylbiguanide side effects and Toxicity
No information avaliable
Phenylethylbiguanide Patient Information
No information avaliable
Phenylethylbiguanide Organisms Affected
Humans and other mammals
