Beta-Phenethylbiguanide
Beta-Phenethylbiguanide Brand names, Beta-Phenethylbiguanide Analogs
- Azucaps
- Beta-Pebg
- Beta-Phenethybiguanide
- Beta-Phenethylbiguanide
- Cronoformin
- D Bretard
- DBI
- DB Comb
- DB-Retard
- DBI Monohydrochloride
- Debeone
- Debinyl
- Diabis
- Dibein
- Dibiraf
- Dibotin
- Dipar
- Feguanide
- Fenfoduron
- Fenformin
- Fenformina
- Fenformina [Inn-Spanish]
- Fenormin
- Glukopostin
- Glyphen
- Insoral
- Lentobetic
- Meltrol
- Meltrol-50
- N-Phenethylbiguanide Hydrochloride
- Normoglucina
- Pedg
- Phenethylbiguanide Hydrochloride
- Phenethyldiguanide
- Phenformin HCl
- Phenformin Hydrochloride
- Phenformine
- Phenformine HCl
- Phenformine [Inn-French]
- Phenforminum [Inn-Latin]
- Phenformix
- Phenoformine Hydrochloride
- Phenylethylbiguanide
- Retardo
Beta-Phenethylbiguanide Brand Names Mixture
- No information avaliable
Beta-Phenethylbiguanide Chemical_Formula
C10H15N5
Beta-Phenethylbiguanide RX_link
No information avaliable
Beta-Phenethylbiguanide fda sheet
Beta-Phenethylbiguanide msds (material safety sheet)
Beta-Phenethylbiguanide Synthesis Reference
Shapiro, Freedman, U.S. pats. 2,961,377, 3,057,780 (1960, 1962 both to U.S.V.)
Beta-Phenethylbiguanide Molecular Weight
205.26 g/mol
Beta-Phenethylbiguanide Melting Point
175-178 oC
Beta-Phenethylbiguanide H2O Solubility
210 mg/mL
Beta-Phenethylbiguanide State
Solid
Beta-Phenethylbiguanide LogP
0.759
Beta-Phenethylbiguanide Dosage Forms
No information avaliable
Beta-Phenethylbiguanide Indication
For the reatment of type II diabetes mellitus.
Beta-Phenethylbiguanide Pharmacology
Used to treat diabetes, phenformin is a biguanide (contains 2 guanidino groups) hypoglycemic agent with actions and uses similar to those of metformin (Glucophage). Both drugs work by (1) decreasing the absorption of glucose by the intestines, (2) decreasing the production of glucose in the liver, and by (3) increasing the body's ability to use insulin more effectively. More specifically, phenformin improves glycemic control by improving insulin sensitivity. Phenformin is generally considered to be associated with an unacceptably high incidence of actic acidosis. In general biguanides should be used only in stable type II diabetics who are free of liver, kidney and cardiovascular problems and who cannot be controlled with diet.
Beta-Phenethylbiguanide Absorption
No information avaliable
Beta-Phenethylbiguanide side effects and Toxicity
No information avaliable
Beta-Phenethylbiguanide Patient Information
No information avaliable
Beta-Phenethylbiguanide Organisms Affected
Humans and other mammals
