D Bretard
D Bretard Brand names, D Bretard Analogs
- Azucaps
- Beta-Pebg
- Beta-Phenethybiguanide
- Beta-Phenethylbiguanide
- Cronoformin
- D Bretard
- DBI
- DB Comb
- DB-Retard
- DBI Monohydrochloride
- Debeone
- Debinyl
- Diabis
- Dibein
- Dibiraf
- Dibotin
- Dipar
- Feguanide
- Fenfoduron
- Fenformin
- Fenformina
- Fenformina [Inn-Spanish]
- Fenormin
- Glukopostin
- Glyphen
- Insoral
- Lentobetic
- Meltrol
- Meltrol-50
- N-Phenethylbiguanide Hydrochloride
- Normoglucina
- Pedg
- Phenethylbiguanide Hydrochloride
- Phenethyldiguanide
- Phenformin HCl
- Phenformin Hydrochloride
- Phenformine
- Phenformine HCl
- Phenformine [Inn-French]
- Phenforminum [Inn-Latin]
- Phenformix
- Phenoformine Hydrochloride
- Phenylethylbiguanide
- Retardo
D Bretard Brand Names Mixture
- No information avaliable
D Bretard Chemical_Formula
C10H15N5
D Bretard RX_link
No information avaliable
D Bretard fda sheet
D Bretard msds (material safety sheet)
D Bretard Synthesis Reference
Shapiro, Freedman, U.S. pats. 2,961,377, 3,057,780 (1960, 1962 both to U.S.V.)
D Bretard Molecular Weight
205.26 g/mol
D Bretard Melting Point
175-178 oC
D Bretard H2O Solubility
210 mg/mL
D Bretard State
Solid
D Bretard LogP
0.759
D Bretard Dosage Forms
No information avaliable
D Bretard Indication
For the reatment of type II diabetes mellitus.
D Bretard Pharmacology
Used to treat diabetes, phenformin is a biguanide (contains 2 guanidino groups) hypoglycemic agent with actions and uses similar to those of metformin (Glucophage). Both drugs work by (1) decreasing the absorption of glucose by the intestines, (2) decreasing the production of glucose in the liver, and by (3) increasing the body's ability to use insulin more effectively. More specifically, phenformin improves glycemic control by improving insulin sensitivity. Phenformin is generally considered to be associated with an unacceptably high incidence of actic acidosis. In general biguanides should be used only in stable type II diabetics who are free of liver, kidney and cardiovascular problems and who cannot be controlled with diet.
D Bretard Absorption
No information avaliable
D Bretard side effects and Toxicity
No information avaliable
D Bretard Patient Information
No information avaliable
D Bretard Organisms Affected
Humans and other mammals
