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D Bretard Brand names, D Bretard Analogs

D Bretard Brand Names Mixture

  • No information avaliable

D Bretard Chemical_Formula


D Bretard RX_link

No information avaliable

D Bretard fda sheet

D Bretard msds (material safety sheet)

D Bretard Synthesis Reference

Shapiro, Freedman, U.S. pats. 2,961,377, 3,057,780 (1960, 1962 both to U.S.V.)

D Bretard Molecular Weight

205.26 g/mol

D Bretard Melting Point

175-178 oC

D Bretard H2O Solubility

210 mg/mL

D Bretard State


D Bretard LogP


D Bretard Dosage Forms

No information avaliable

D Bretard Indication

For the reatment of type II diabetes mellitus.

D Bretard Pharmacology

Used to treat diabetes, phenformin is a biguanide (contains 2 guanidino groups) hypoglycemic agent with actions and uses similar to those of metformin (Glucophage). Both drugs work by (1) decreasing the absorption of glucose by the intestines, (2) decreasing the production of glucose in the liver, and by (3) increasing the body's ability to use insulin more effectively. More specifically, phenformin improves glycemic control by improving insulin sensitivity. Phenformin is generally considered to be associated with an unacceptably high incidence of actic acidosis. In general biguanides should be used only in stable type II diabetics who are free of liver, kidney and cardiovascular problems and who cannot be controlled with diet.

D Bretard Absorption

No information avaliable

D Bretard side effects and Toxicity

No information avaliable

D Bretard Patient Information

No information avaliable

D Bretard Organisms Affected

Humans and other mammals