DB-Retard
DB-Retard Brand names, DB-Retard Analogs
- Azucaps
- Beta-Pebg
- Beta-Phenethybiguanide
- Beta-Phenethylbiguanide
- Cronoformin
- D Bretard
- DBI
- DB Comb
- DB-Retard
- DBI Monohydrochloride
- Debeone
- Debinyl
- Diabis
- Dibein
- Dibiraf
- Dibotin
- Dipar
- Feguanide
- Fenfoduron
- Fenformin
- Fenformina
- Fenformina [Inn-Spanish]
- Fenormin
- Glukopostin
- Glyphen
- Insoral
- Lentobetic
- Meltrol
- Meltrol-50
- N-Phenethylbiguanide Hydrochloride
- Normoglucina
- Pedg
- Phenethylbiguanide Hydrochloride
- Phenethyldiguanide
- Phenformin HCl
- Phenformin Hydrochloride
- Phenformine
- Phenformine HCl
- Phenformine [Inn-French]
- Phenforminum [Inn-Latin]
- Phenformix
- Phenoformine Hydrochloride
- Phenylethylbiguanide
- Retardo
DB-Retard Brand Names Mixture
- No information avaliable
DB-Retard Chemical_Formula
C10H15N5
DB-Retard RX_link
No information avaliable
DB-Retard fda sheet
DB-Retard msds (material safety sheet)
DB-Retard Synthesis Reference
Shapiro, Freedman, U.S. pats. 2,961,377, 3,057,780 (1960, 1962 both to U.S.V.)
DB-Retard Molecular Weight
205.26 g/mol
DB-Retard Melting Point
175-178 oC
DB-Retard H2O Solubility
210 mg/mL
DB-Retard State
Solid
DB-Retard LogP
0.759
DB-Retard Dosage Forms
No information avaliable
DB-Retard Indication
For the reatment of type II diabetes mellitus.
DB-Retard Pharmacology
Used to treat diabetes, phenformin is a biguanide (contains 2 guanidino groups) hypoglycemic agent with actions and uses similar to those of metformin (Glucophage). Both drugs work by (1) decreasing the absorption of glucose by the intestines, (2) decreasing the production of glucose in the liver, and by (3) increasing the body's ability to use insulin more effectively. More specifically, phenformin improves glycemic control by improving insulin sensitivity. Phenformin is generally considered to be associated with an unacceptably high incidence of actic acidosis. In general biguanides should be used only in stable type II diabetics who are free of liver, kidney and cardiovascular problems and who cannot be controlled with diet.
DB-Retard Absorption
No information avaliable
DB-Retard side effects and Toxicity
No information avaliable
DB-Retard Patient Information
No information avaliable
DB-Retard Organisms Affected
Humans and other mammals
