Beta-Phenethybiguanide
Beta-Phenethybiguanide Brand names, Beta-Phenethybiguanide Analogs
- Azucaps
- Beta-Pebg
- Beta-Phenethybiguanide
- Beta-Phenethylbiguanide
- Cronoformin
- D Bretard
- DBI
- DB Comb
- DB-Retard
- DBI Monohydrochloride
- Debeone
- Debinyl
- Diabis
- Dibein
- Dibiraf
- Dibotin
- Dipar
- Feguanide
- Fenfoduron
- Fenformin
- Fenformina
- Fenformina [Inn-Spanish]
- Fenormin
- Glukopostin
- Glyphen
- Insoral
- Lentobetic
- Meltrol
- Meltrol-50
- N-Phenethylbiguanide Hydrochloride
- Normoglucina
- Pedg
- Phenethylbiguanide Hydrochloride
- Phenethyldiguanide
- Phenformin HCl
- Phenformin Hydrochloride
- Phenformine
- Phenformine HCl
- Phenformine [Inn-French]
- Phenforminum [Inn-Latin]
- Phenformix
- Phenoformine Hydrochloride
- Phenylethylbiguanide
- Retardo
Beta-Phenethybiguanide Brand Names Mixture
- No information avaliable
Beta-Phenethybiguanide Chemical_Formula
C10H15N5
Beta-Phenethybiguanide RX_link
No information avaliable
Beta-Phenethybiguanide fda sheet
Beta-Phenethybiguanide msds (material safety sheet)
Beta-Phenethybiguanide Synthesis Reference
Shapiro, Freedman, U.S. pats. 2,961,377, 3,057,780 (1960, 1962 both to U.S.V.)
Beta-Phenethybiguanide Molecular Weight
205.26 g/mol
Beta-Phenethybiguanide Melting Point
175-178 oC
Beta-Phenethybiguanide H2O Solubility
210 mg/mL
Beta-Phenethybiguanide State
Solid
Beta-Phenethybiguanide LogP
0.759
Beta-Phenethybiguanide Dosage Forms
No information avaliable
Beta-Phenethybiguanide Indication
For the reatment of type II diabetes mellitus.
Beta-Phenethybiguanide Pharmacology
Used to treat diabetes, phenformin is a biguanide (contains 2 guanidino groups) hypoglycemic agent with actions and uses similar to those of metformin (Glucophage). Both drugs work by (1) decreasing the absorption of glucose by the intestines, (2) decreasing the production of glucose in the liver, and by (3) increasing the body's ability to use insulin more effectively. More specifically, phenformin improves glycemic control by improving insulin sensitivity. Phenformin is generally considered to be associated with an unacceptably high incidence of actic acidosis. In general biguanides should be used only in stable type II diabetics who are free of liver, kidney and cardiovascular problems and who cannot be controlled with diet.
Beta-Phenethybiguanide Absorption
No information avaliable
Beta-Phenethybiguanide side effects and Toxicity
No information avaliable
Beta-Phenethybiguanide Patient Information
No information avaliable
Beta-Phenethybiguanide Organisms Affected
Humans and other mammals
