Phenforminum [Inn-Latin] en es it fr

Phenforminum [Inn-Latin] Brand names, Phenforminum [Inn-Latin] Analogs

Phenforminum [Inn-Latin] Brand Names Mixture

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Phenforminum [Inn-Latin] Chemical_Formula


Phenforminum [Inn-Latin] RX_link

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Phenforminum [Inn-Latin] fda sheet

Phenforminum [Inn-Latin] msds (material safety sheet)

Phenforminum [Inn-Latin] Synthesis Reference

Shapiro, Freedman, U.S. pats. 2,961,377, 3,057,780 (1960, 1962 both to U.S.V.)

Phenforminum [Inn-Latin] Molecular Weight

205.26 g/mol

Phenforminum [Inn-Latin] Melting Point

175-178 oC

Phenforminum [Inn-Latin] H2O Solubility

210 mg/mL

Phenforminum [Inn-Latin] State


Phenforminum [Inn-Latin] LogP


Phenforminum [Inn-Latin] Dosage Forms

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Phenforminum [Inn-Latin] Indication

For the reatment of type II diabetes mellitus.

Phenforminum [Inn-Latin] Pharmacology

Used to treat diabetes, phenformin is a biguanide (contains 2 guanidino groups) hypoglycemic agent with actions and uses similar to those of metformin (Glucophage). Both drugs work by (1) decreasing the absorption of glucose by the intestines, (2) decreasing the production of glucose in the liver, and by (3) increasing the body's ability to use insulin more effectively. More specifically, phenformin improves glycemic control by improving insulin sensitivity. Phenformin is generally considered to be associated with an unacceptably high incidence of actic acidosis. In general biguanides should be used only in stable type II diabetics who are free of liver, kidney and cardiovascular problems and who cannot be controlled with diet.

Phenforminum [Inn-Latin] Absorption

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Phenforminum [Inn-Latin] side effects and Toxicity

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Phenforminum [Inn-Latin] Patient Information

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Phenforminum [Inn-Latin] Organisms Affected

Humans and other mammals