Retardo
Retardo Brand names, Retardo Analogs
- Azucaps
- Beta-Pebg
- Beta-Phenethybiguanide
- Beta-Phenethylbiguanide
- Cronoformin
- D Bretard
- DBI
- DB Comb
- DB-Retard
- DBI Monohydrochloride
- Debeone
- Debinyl
- Diabis
- Dibein
- Dibiraf
- Dibotin
- Dipar
- Feguanide
- Fenfoduron
- Fenformin
- Fenformina
- Fenformina [Inn-Spanish]
- Fenormin
- Glukopostin
- Glyphen
- Insoral
- Lentobetic
- Meltrol
- Meltrol-50
- N-Phenethylbiguanide Hydrochloride
- Normoglucina
- Pedg
- Phenethylbiguanide Hydrochloride
- Phenethyldiguanide
- Phenformin HCl
- Phenformin Hydrochloride
- Phenformine
- Phenformine HCl
- Phenformine [Inn-French]
- Phenforminum [Inn-Latin]
- Phenformix
- Phenoformine Hydrochloride
- Phenylethylbiguanide
- Retardo
Retardo Brand Names Mixture
- No information avaliable
Retardo Chemical_Formula
C10H15N5
Retardo RX_link
No information avaliable
Retardo fda sheet
Retardo msds (material safety sheet)
Retardo Synthesis Reference
Shapiro, Freedman, U.S. pats. 2,961,377, 3,057,780 (1960, 1962 both to U.S.V.)
Retardo Molecular Weight
205.26 g/mol
Retardo Melting Point
175-178 oC
Retardo H2O Solubility
210 mg/mL
Retardo State
Solid
Retardo LogP
0.759
Retardo Dosage Forms
No information avaliable
Retardo Indication
For the reatment of type II diabetes mellitus.
Retardo Pharmacology
Used to treat diabetes, phenformin is a biguanide (contains 2 guanidino groups) hypoglycemic agent with actions and uses similar to those of metformin (Glucophage). Both drugs work by (1) decreasing the absorption of glucose by the intestines, (2) decreasing the production of glucose in the liver, and by (3) increasing the body's ability to use insulin more effectively. More specifically, phenformin improves glycemic control by improving insulin sensitivity. Phenformin is generally considered to be associated with an unacceptably high incidence of actic acidosis. In general biguanides should be used only in stable type II diabetics who are free of liver, kidney and cardiovascular problems and who cannot be controlled with diet.
Retardo Absorption
No information avaliable
Retardo side effects and Toxicity
No information avaliable
Retardo Patient Information
No information avaliable
Retardo Organisms Affected
Humans and other mammals
