Phenformine HCl
Phenformine HCl Brand names, Phenformine HCl Analogs
- Azucaps
- Beta-Pebg
- Beta-Phenethybiguanide
- Beta-Phenethylbiguanide
- Cronoformin
- D Bretard
- DBI
- DB Comb
- DB-Retard
- DBI Monohydrochloride
- Debeone
- Debinyl
- Diabis
- Dibein
- Dibiraf
- Dibotin
- Dipar
- Feguanide
- Fenfoduron
- Fenformin
- Fenformina
- Fenformina [Inn-Spanish]
- Fenormin
- Glukopostin
- Glyphen
- Insoral
- Lentobetic
- Meltrol
- Meltrol-50
- N-Phenethylbiguanide Hydrochloride
- Normoglucina
- Pedg
- Phenethylbiguanide Hydrochloride
- Phenethyldiguanide
- Phenformin HCl
- Phenformin Hydrochloride
- Phenformine
- Phenformine HCl
- Phenformine [Inn-French]
- Phenforminum [Inn-Latin]
- Phenformix
- Phenoformine Hydrochloride
- Phenylethylbiguanide
- Retardo
Phenformine HCl Brand Names Mixture
- No information avaliable
Phenformine HCl Chemical_Formula
C10H15N5
Phenformine HCl RX_link
No information avaliable
Phenformine HCl fda sheet
Phenformine HCl msds (material safety sheet)
Phenformine HCl Synthesis Reference
Shapiro, Freedman, U.S. pats. 2,961,377, 3,057,780 (1960, 1962 both to U.S.V.)
Phenformine HCl Molecular Weight
205.26 g/mol
Phenformine HCl Melting Point
175-178 oC
Phenformine HCl H2O Solubility
210 mg/mL
Phenformine HCl State
Solid
Phenformine HCl LogP
0.759
Phenformine HCl Dosage Forms
No information avaliable
Phenformine HCl Indication
For the reatment of type II diabetes mellitus.
Phenformine HCl Pharmacology
Used to treat diabetes, phenformin is a biguanide (contains 2 guanidino groups) hypoglycemic agent with actions and uses similar to those of metformin (Glucophage). Both drugs work by (1) decreasing the absorption of glucose by the intestines, (2) decreasing the production of glucose in the liver, and by (3) increasing the body's ability to use insulin more effectively. More specifically, phenformin improves glycemic control by improving insulin sensitivity. Phenformin is generally considered to be associated with an unacceptably high incidence of actic acidosis. In general biguanides should be used only in stable type II diabetics who are free of liver, kidney and cardiovascular problems and who cannot be controlled with diet.
Phenformine HCl Absorption
No information avaliable
Phenformine HCl side effects and Toxicity
No information avaliable
Phenformine HCl Patient Information
No information avaliable
Phenformine HCl Organisms Affected
Humans and other mammals
