Glyphen
Glyphen Brand names, Glyphen Analogs
- Azucaps
- Beta-Pebg
- Beta-Phenethybiguanide
- Beta-Phenethylbiguanide
- Cronoformin
- D Bretard
- DBI
- DB Comb
- DB-Retard
- DBI Monohydrochloride
- Debeone
- Debinyl
- Diabis
- Dibein
- Dibiraf
- Dibotin
- Dipar
- Feguanide
- Fenfoduron
- Fenformin
- Fenformina
- Fenformina [Inn-Spanish]
- Fenormin
- Glukopostin
- Glyphen
- Insoral
- Lentobetic
- Meltrol
- Meltrol-50
- N-Phenethylbiguanide Hydrochloride
- Normoglucina
- Pedg
- Phenethylbiguanide Hydrochloride
- Phenethyldiguanide
- Phenformin HCl
- Phenformin Hydrochloride
- Phenformine
- Phenformine HCl
- Phenformine [Inn-French]
- Phenforminum [Inn-Latin]
- Phenformix
- Phenoformine Hydrochloride
- Phenylethylbiguanide
- Retardo
Glyphen Brand Names Mixture
- No information avaliable
Glyphen Chemical_Formula
C10H15N5
Glyphen RX_link
No information avaliable
Glyphen fda sheet
Glyphen msds (material safety sheet)
Glyphen Synthesis Reference
Shapiro, Freedman, U.S. pats. 2,961,377, 3,057,780 (1960, 1962 both to U.S.V.)
Glyphen Molecular Weight
205.26 g/mol
Glyphen Melting Point
175-178 oC
Glyphen H2O Solubility
210 mg/mL
Glyphen State
Solid
Glyphen LogP
0.759
Glyphen Dosage Forms
No information avaliable
Glyphen Indication
For the reatment of type II diabetes mellitus.
Glyphen Pharmacology
Used to treat diabetes, phenformin is a biguanide (contains 2 guanidino groups) hypoglycemic agent with actions and uses similar to those of metformin (Glucophage). Both drugs work by (1) decreasing the absorption of glucose by the intestines, (2) decreasing the production of glucose in the liver, and by (3) increasing the body's ability to use insulin more effectively. More specifically, phenformin improves glycemic control by improving insulin sensitivity. Phenformin is generally considered to be associated with an unacceptably high incidence of actic acidosis. In general biguanides should be used only in stable type II diabetics who are free of liver, kidney and cardiovascular problems and who cannot be controlled with diet.
Glyphen Absorption
No information avaliable
Glyphen side effects and Toxicity
No information avaliable
Glyphen Patient Information
No information avaliable
Glyphen Organisms Affected
Humans and other mammals
