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Glyphen Brand names, Glyphen Analogs

Glyphen Brand Names Mixture

  • No information avaliable

Glyphen Chemical_Formula


Glyphen RX_link

No information avaliable

Glyphen fda sheet

Glyphen msds (material safety sheet)

Glyphen Synthesis Reference

Shapiro, Freedman, U.S. pats. 2,961,377, 3,057,780 (1960, 1962 both to U.S.V.)

Glyphen Molecular Weight

205.26 g/mol

Glyphen Melting Point

175-178 oC

Glyphen H2O Solubility

210 mg/mL

Glyphen State


Glyphen LogP


Glyphen Dosage Forms

No information avaliable

Glyphen Indication

For the reatment of type II diabetes mellitus.

Glyphen Pharmacology

Used to treat diabetes, phenformin is a biguanide (contains 2 guanidino groups) hypoglycemic agent with actions and uses similar to those of metformin (Glucophage). Both drugs work by (1) decreasing the absorption of glucose by the intestines, (2) decreasing the production of glucose in the liver, and by (3) increasing the body's ability to use insulin more effectively. More specifically, phenformin improves glycemic control by improving insulin sensitivity. Phenformin is generally considered to be associated with an unacceptably high incidence of actic acidosis. In general biguanides should be used only in stable type II diabetics who are free of liver, kidney and cardiovascular problems and who cannot be controlled with diet.

Glyphen Absorption

No information avaliable

Glyphen side effects and Toxicity

No information avaliable

Glyphen Patient Information

No information avaliable

Glyphen Organisms Affected

Humans and other mammals