Meltrol
Meltrol Brand names, Meltrol Analogs
- Azucaps
- Beta-Pebg
- Beta-Phenethybiguanide
- Beta-Phenethylbiguanide
- Cronoformin
- D Bretard
- DBI
- DB Comb
- DB-Retard
- DBI Monohydrochloride
- Debeone
- Debinyl
- Diabis
- Dibein
- Dibiraf
- Dibotin
- Dipar
- Feguanide
- Fenfoduron
- Fenformin
- Fenformina
- Fenformina [Inn-Spanish]
- Fenormin
- Glukopostin
- Glyphen
- Insoral
- Lentobetic
- Meltrol
- Meltrol-50
- N-Phenethylbiguanide Hydrochloride
- Normoglucina
- Pedg
- Phenethylbiguanide Hydrochloride
- Phenethyldiguanide
- Phenformin HCl
- Phenformin Hydrochloride
- Phenformine
- Phenformine HCl
- Phenformine [Inn-French]
- Phenforminum [Inn-Latin]
- Phenformix
- Phenoformine Hydrochloride
- Phenylethylbiguanide
- Retardo
Meltrol Brand Names Mixture
- No information avaliable
Meltrol Chemical_Formula
C10H15N5
Meltrol RX_link
No information avaliable
Meltrol fda sheet
Meltrol msds (material safety sheet)
Meltrol Synthesis Reference
Shapiro, Freedman, U.S. pats. 2,961,377, 3,057,780 (1960, 1962 both to U.S.V.)
Meltrol Molecular Weight
205.26 g/mol
Meltrol Melting Point
175-178 oC
Meltrol H2O Solubility
210 mg/mL
Meltrol State
Solid
Meltrol LogP
0.759
Meltrol Dosage Forms
No information avaliable
Meltrol Indication
For the reatment of type II diabetes mellitus.
Meltrol Pharmacology
Used to treat diabetes, phenformin is a biguanide (contains 2 guanidino groups) hypoglycemic agent with actions and uses similar to those of metformin (Glucophage). Both drugs work by (1) decreasing the absorption of glucose by the intestines, (2) decreasing the production of glucose in the liver, and by (3) increasing the body's ability to use insulin more effectively. More specifically, phenformin improves glycemic control by improving insulin sensitivity. Phenformin is generally considered to be associated with an unacceptably high incidence of actic acidosis. In general biguanides should be used only in stable type II diabetics who are free of liver, kidney and cardiovascular problems and who cannot be controlled with diet.
Meltrol Absorption
No information avaliable
Meltrol side effects and Toxicity
No information avaliable
Meltrol Patient Information
No information avaliable
Meltrol Organisms Affected
Humans and other mammals
