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DBI Brand names, DBI Analogs

DBI Brand Names Mixture

  • No information avaliable

DBI Chemical_Formula


DBI RX_link

No information avaliable

DBI fda sheet

DBI msds (material safety sheet)

DBI Synthesis Reference

Shapiro, Freedman, U.S. pats. 2,961,377, 3,057,780 (1960, 1962 both to U.S.V.)

DBI Molecular Weight

205.26 g/mol

DBI Melting Point

175-178 oC

DBI H2O Solubility

210 mg/mL

DBI State




DBI Dosage Forms

No information avaliable

DBI Indication

For the reatment of type II diabetes mellitus.

DBI Pharmacology

Used to treat diabetes, phenformin is a biguanide (contains 2 guanidino groups) hypoglycemic agent with actions and uses similar to those of metformin (Glucophage). Both drugs work by (1) decreasing the absorption of glucose by the intestines, (2) decreasing the production of glucose in the liver, and by (3) increasing the body's ability to use insulin more effectively. More specifically, phenformin improves glycemic control by improving insulin sensitivity. Phenformin is generally considered to be associated with an unacceptably high incidence of actic acidosis. In general biguanides should be used only in stable type II diabetics who are free of liver, kidney and cardiovascular problems and who cannot be controlled with diet.

DBI Absorption

No information avaliable

DBI side effects and Toxicity

No information avaliable

DBI Patient Information

No information avaliable

DBI Organisms Affected

Humans and other mammals