Dibiraf
Dibiraf Brand names, Dibiraf Analogs
- Azucaps
- Beta-Pebg
- Beta-Phenethybiguanide
- Beta-Phenethylbiguanide
- Cronoformin
- D Bretard
- DBI
- DB Comb
- DB-Retard
- DBI Monohydrochloride
- Debeone
- Debinyl
- Diabis
- Dibein
- Dibiraf
- Dibotin
- Dipar
- Feguanide
- Fenfoduron
- Fenformin
- Fenformina
- Fenformina [Inn-Spanish]
- Fenormin
- Glukopostin
- Glyphen
- Insoral
- Lentobetic
- Meltrol
- Meltrol-50
- N-Phenethylbiguanide Hydrochloride
- Normoglucina
- Pedg
- Phenethylbiguanide Hydrochloride
- Phenethyldiguanide
- Phenformin HCl
- Phenformin Hydrochloride
- Phenformine
- Phenformine HCl
- Phenformine [Inn-French]
- Phenforminum [Inn-Latin]
- Phenformix
- Phenoformine Hydrochloride
- Phenylethylbiguanide
- Retardo
Dibiraf Brand Names Mixture
- No information avaliable
Dibiraf Chemical_Formula
C10H15N5
Dibiraf RX_link
No information avaliable
Dibiraf fda sheet
Dibiraf msds (material safety sheet)
Dibiraf Synthesis Reference
Shapiro, Freedman, U.S. pats. 2,961,377, 3,057,780 (1960, 1962 both to U.S.V.)
Dibiraf Molecular Weight
205.26 g/mol
Dibiraf Melting Point
175-178 oC
Dibiraf H2O Solubility
210 mg/mL
Dibiraf State
Solid
Dibiraf LogP
0.759
Dibiraf Dosage Forms
No information avaliable
Dibiraf Indication
For the reatment of type II diabetes mellitus.
Dibiraf Pharmacology
Used to treat diabetes, phenformin is a biguanide (contains 2 guanidino groups) hypoglycemic agent with actions and uses similar to those of metformin (Glucophage). Both drugs work by (1) decreasing the absorption of glucose by the intestines, (2) decreasing the production of glucose in the liver, and by (3) increasing the body's ability to use insulin more effectively. More specifically, phenformin improves glycemic control by improving insulin sensitivity. Phenformin is generally considered to be associated with an unacceptably high incidence of actic acidosis. In general biguanides should be used only in stable type II diabetics who are free of liver, kidney and cardiovascular problems and who cannot be controlled with diet.
Dibiraf Absorption
No information avaliable
Dibiraf side effects and Toxicity
No information avaliable
Dibiraf Patient Information
No information avaliable
Dibiraf Organisms Affected
Humans and other mammals
