Azucaps
Brand names,
Azucaps
Analogs
Azucaps
Brand Names Mixture
Azucaps
Chemical_Formula
C10H15N5
Azucaps
RX_link
No information avaliable
Azucaps
fda sheet
Azucaps
msds (material safety sheet)
Azucaps
Synthesis Reference
Shapiro, Freedman, U.S. pats. 2,961,377, 3,057,780 (1960, 1962 both to U.S.V.)
Azucaps
Molecular Weight
205.26 g/mol
Azucaps
Melting Point
175-178 oC
Azucaps
H2O Solubility
210 mg/mL
Azucaps
State
Solid
Azucaps
LogP
0.759
Azucaps
Dosage Forms
No information avaliable
Azucaps
Indication
For the reatment of type II diabetes mellitus.
Azucaps
Pharmacology
Used to treat diabetes, phenformin is a biguanide (contains 2 guanidino groups) hypoglycemic agent with actions and uses similar to those of metformin (Glucophage). Both drugs work by (1) decreasing the absorption of glucose by the intestines, (2) decreasing the production of glucose in the liver, and by (3) increasing the body's ability to use insulin more effectively. More specifically, phenformin improves glycemic control by improving insulin sensitivity. Phenformin is generally considered to be associated with an unacceptably high incidence of actic acidosis. In general biguanides should be used only in stable type II diabetics who are free of liver, kidney and cardiovascular problems and who cannot be controlled with diet.
Azucaps
Absorption
No information avaliable
Azucaps
side effects and Toxicity
No information avaliable
Azucaps
Patient Information
No information avaliable
Azucaps
Organisms Affected
Humans and other mammals