Debinyl
Debinyl Brand names, Debinyl Analogs
- Azucaps
- Beta-Pebg
- Beta-Phenethybiguanide
- Beta-Phenethylbiguanide
- Cronoformin
- D Bretard
- DBI
- DB Comb
- DB-Retard
- DBI Monohydrochloride
- Debeone
- Debinyl
- Diabis
- Dibein
- Dibiraf
- Dibotin
- Dipar
- Feguanide
- Fenfoduron
- Fenformin
- Fenformina
- Fenformina [Inn-Spanish]
- Fenormin
- Glukopostin
- Glyphen
- Insoral
- Lentobetic
- Meltrol
- Meltrol-50
- N-Phenethylbiguanide Hydrochloride
- Normoglucina
- Pedg
- Phenethylbiguanide Hydrochloride
- Phenethyldiguanide
- Phenformin HCl
- Phenformin Hydrochloride
- Phenformine
- Phenformine HCl
- Phenformine [Inn-French]
- Phenforminum [Inn-Latin]
- Phenformix
- Phenoformine Hydrochloride
- Phenylethylbiguanide
- Retardo
Debinyl Brand Names Mixture
- No information avaliable
Debinyl Chemical_Formula
C10H15N5
Debinyl RX_link
No information avaliable
Debinyl fda sheet
Debinyl msds (material safety sheet)
Debinyl Synthesis Reference
Shapiro, Freedman, U.S. pats. 2,961,377, 3,057,780 (1960, 1962 both to U.S.V.)
Debinyl Molecular Weight
205.26 g/mol
Debinyl Melting Point
175-178 oC
Debinyl H2O Solubility
210 mg/mL
Debinyl State
Solid
Debinyl LogP
0.759
Debinyl Dosage Forms
No information avaliable
Debinyl Indication
For the reatment of type II diabetes mellitus.
Debinyl Pharmacology
Used to treat diabetes, phenformin is a biguanide (contains 2 guanidino groups) hypoglycemic agent with actions and uses similar to those of metformin (Glucophage). Both drugs work by (1) decreasing the absorption of glucose by the intestines, (2) decreasing the production of glucose in the liver, and by (3) increasing the body's ability to use insulin more effectively. More specifically, phenformin improves glycemic control by improving insulin sensitivity. Phenformin is generally considered to be associated with an unacceptably high incidence of actic acidosis. In general biguanides should be used only in stable type II diabetics who are free of liver, kidney and cardiovascular problems and who cannot be controlled with diet.
Debinyl Absorption
No information avaliable
Debinyl side effects and Toxicity
No information avaliable
Debinyl Patient Information
No information avaliable
Debinyl Organisms Affected
Humans and other mammals
