DBI Monohydrochloride
DBI Monohydrochloride Brand names, DBI Monohydrochloride Analogs
- Azucaps
- Beta-Pebg
- Beta-Phenethybiguanide
- Beta-Phenethylbiguanide
- Cronoformin
- D Bretard
- DBI
- DB Comb
- DB-Retard
- DBI Monohydrochloride
- Debeone
- Debinyl
- Diabis
- Dibein
- Dibiraf
- Dibotin
- Dipar
- Feguanide
- Fenfoduron
- Fenformin
- Fenformina
- Fenformina [Inn-Spanish]
- Fenormin
- Glukopostin
- Glyphen
- Insoral
- Lentobetic
- Meltrol
- Meltrol-50
- N-Phenethylbiguanide Hydrochloride
- Normoglucina
- Pedg
- Phenethylbiguanide Hydrochloride
- Phenethyldiguanide
- Phenformin HCl
- Phenformin Hydrochloride
- Phenformine
- Phenformine HCl
- Phenformine [Inn-French]
- Phenforminum [Inn-Latin]
- Phenformix
- Phenoformine Hydrochloride
- Phenylethylbiguanide
- Retardo
DBI Monohydrochloride Brand Names Mixture
- No information avaliable
DBI Monohydrochloride Chemical_Formula
C10H15N5
DBI Monohydrochloride RX_link
No information avaliable
DBI Monohydrochloride fda sheet
DBI Monohydrochloride msds (material safety sheet)
DBI Monohydrochloride Synthesis Reference
Shapiro, Freedman, U.S. pats. 2,961,377, 3,057,780 (1960, 1962 both to U.S.V.)
DBI Monohydrochloride Molecular Weight
205.26 g/mol
DBI Monohydrochloride Melting Point
175-178 oC
DBI Monohydrochloride H2O Solubility
210 mg/mL
DBI Monohydrochloride State
Solid
DBI Monohydrochloride LogP
0.759
DBI Monohydrochloride Dosage Forms
No information avaliable
DBI Monohydrochloride Indication
For the reatment of type II diabetes mellitus.
DBI Monohydrochloride Pharmacology
Used to treat diabetes, phenformin is a biguanide (contains 2 guanidino groups) hypoglycemic agent with actions and uses similar to those of metformin (Glucophage). Both drugs work by (1) decreasing the absorption of glucose by the intestines, (2) decreasing the production of glucose in the liver, and by (3) increasing the body's ability to use insulin more effectively. More specifically, phenformin improves glycemic control by improving insulin sensitivity. Phenformin is generally considered to be associated with an unacceptably high incidence of actic acidosis. In general biguanides should be used only in stable type II diabetics who are free of liver, kidney and cardiovascular problems and who cannot be controlled with diet.
DBI Monohydrochloride Absorption
No information avaliable
DBI Monohydrochloride side effects and Toxicity
No information avaliable
DBI Monohydrochloride Patient Information
No information avaliable
DBI Monohydrochloride Organisms Affected
Humans and other mammals
