Beta-Pebg
Brand names,
Beta-Pebg
Analogs
Beta-Pebg
Brand Names Mixture
Beta-Pebg
Chemical_Formula
C10H15N5
Beta-Pebg
RX_link
No information avaliable
Beta-Pebg
fda sheet
Beta-Pebg
msds (material safety sheet)
Beta-Pebg
Synthesis Reference
Shapiro, Freedman, U.S. pats. 2,961,377, 3,057,780 (1960, 1962 both to U.S.V.)
Beta-Pebg
Molecular Weight
205.26 g/mol
Beta-Pebg
Melting Point
175-178 oC
Beta-Pebg
H2O Solubility
210 mg/mL
Beta-Pebg
State
Solid
Beta-Pebg
LogP
0.759
Beta-Pebg
Dosage Forms
No information avaliable
Beta-Pebg
Indication
For the reatment of type II diabetes mellitus.
Beta-Pebg
Pharmacology
Used to treat diabetes, phenformin is a biguanide (contains 2 guanidino groups) hypoglycemic agent with actions and uses similar to those of metformin (Glucophage). Both drugs work by (1) decreasing the absorption of glucose by the intestines, (2) decreasing the production of glucose in the liver, and by (3) increasing the body's ability to use insulin more effectively. More specifically, phenformin improves glycemic control by improving insulin sensitivity. Phenformin is generally considered to be associated with an unacceptably high incidence of actic acidosis. In general biguanides should be used only in stable type II diabetics who are free of liver, kidney and cardiovascular problems and who cannot be controlled with diet.
Beta-Pebg
Absorption
No information avaliable
Beta-Pebg
side effects and Toxicity
No information avaliable
Beta-Pebg
Patient Information
No information avaliable
Beta-Pebg
Organisms Affected
Humans and other mammals