Lentobetic
Lentobetic Brand names, Lentobetic Analogs
- Azucaps
- Beta-Pebg
- Beta-Phenethybiguanide
- Beta-Phenethylbiguanide
- Cronoformin
- D Bretard
- DBI
- DB Comb
- DB-Retard
- DBI Monohydrochloride
- Debeone
- Debinyl
- Diabis
- Dibein
- Dibiraf
- Dibotin
- Dipar
- Feguanide
- Fenfoduron
- Fenformin
- Fenformina
- Fenformina [Inn-Spanish]
- Fenormin
- Glukopostin
- Glyphen
- Insoral
- Lentobetic
- Meltrol
- Meltrol-50
- N-Phenethylbiguanide Hydrochloride
- Normoglucina
- Pedg
- Phenethylbiguanide Hydrochloride
- Phenethyldiguanide
- Phenformin HCl
- Phenformin Hydrochloride
- Phenformine
- Phenformine HCl
- Phenformine [Inn-French]
- Phenforminum [Inn-Latin]
- Phenformix
- Phenoformine Hydrochloride
- Phenylethylbiguanide
- Retardo
Lentobetic Brand Names Mixture
- No information avaliable
Lentobetic Chemical_Formula
C10H15N5
Lentobetic RX_link
No information avaliable
Lentobetic fda sheet
Lentobetic msds (material safety sheet)
Lentobetic Synthesis Reference
Shapiro, Freedman, U.S. pats. 2,961,377, 3,057,780 (1960, 1962 both to U.S.V.)
Lentobetic Molecular Weight
205.26 g/mol
Lentobetic Melting Point
175-178 oC
Lentobetic H2O Solubility
210 mg/mL
Lentobetic State
Solid
Lentobetic LogP
0.759
Lentobetic Dosage Forms
No information avaliable
Lentobetic Indication
For the reatment of type II diabetes mellitus.
Lentobetic Pharmacology
Used to treat diabetes, phenformin is a biguanide (contains 2 guanidino groups) hypoglycemic agent with actions and uses similar to those of metformin (Glucophage). Both drugs work by (1) decreasing the absorption of glucose by the intestines, (2) decreasing the production of glucose in the liver, and by (3) increasing the body's ability to use insulin more effectively. More specifically, phenformin improves glycemic control by improving insulin sensitivity. Phenformin is generally considered to be associated with an unacceptably high incidence of actic acidosis. In general biguanides should be used only in stable type II diabetics who are free of liver, kidney and cardiovascular problems and who cannot be controlled with diet.
Lentobetic Absorption
No information avaliable
Lentobetic side effects and Toxicity
No information avaliable
Lentobetic Patient Information
No information avaliable
Lentobetic Organisms Affected
Humans and other mammals
