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Phenethyldiguanide Brand names, Phenethyldiguanide Analogs

Phenethyldiguanide Brand Names Mixture

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Phenethyldiguanide Chemical_Formula


Phenethyldiguanide RX_link

No information avaliable

Phenethyldiguanide fda sheet

Phenethyldiguanide msds (material safety sheet)

Phenethyldiguanide Synthesis Reference

Shapiro, Freedman, U.S. pats. 2,961,377, 3,057,780 (1960, 1962 both to U.S.V.)

Phenethyldiguanide Molecular Weight

205.26 g/mol

Phenethyldiguanide Melting Point

175-178 oC

Phenethyldiguanide H2O Solubility

210 mg/mL

Phenethyldiguanide State


Phenethyldiguanide LogP


Phenethyldiguanide Dosage Forms

No information avaliable

Phenethyldiguanide Indication

For the reatment of type II diabetes mellitus.

Phenethyldiguanide Pharmacology

Used to treat diabetes, phenformin is a biguanide (contains 2 guanidino groups) hypoglycemic agent with actions and uses similar to those of metformin (Glucophage). Both drugs work by (1) decreasing the absorption of glucose by the intestines, (2) decreasing the production of glucose in the liver, and by (3) increasing the body's ability to use insulin more effectively. More specifically, phenformin improves glycemic control by improving insulin sensitivity. Phenformin is generally considered to be associated with an unacceptably high incidence of actic acidosis. In general biguanides should be used only in stable type II diabetics who are free of liver, kidney and cardiovascular problems and who cannot be controlled with diet.

Phenethyldiguanide Absorption

No information avaliable

Phenethyldiguanide side effects and Toxicity

No information avaliable

Phenethyldiguanide Patient Information

No information avaliable

Phenethyldiguanide Organisms Affected

Humans and other mammals