Phenethyldiguanide
Phenethyldiguanide Brand names, Phenethyldiguanide Analogs
- Azucaps
- Beta-Pebg
- Beta-Phenethybiguanide
- Beta-Phenethylbiguanide
- Cronoformin
- D Bretard
- DBI
- DB Comb
- DB-Retard
- DBI Monohydrochloride
- Debeone
- Debinyl
- Diabis
- Dibein
- Dibiraf
- Dibotin
- Dipar
- Feguanide
- Fenfoduron
- Fenformin
- Fenformina
- Fenformina [Inn-Spanish]
- Fenormin
- Glukopostin
- Glyphen
- Insoral
- Lentobetic
- Meltrol
- Meltrol-50
- N-Phenethylbiguanide Hydrochloride
- Normoglucina
- Pedg
- Phenethylbiguanide Hydrochloride
- Phenethyldiguanide
- Phenformin HCl
- Phenformin Hydrochloride
- Phenformine
- Phenformine HCl
- Phenformine [Inn-French]
- Phenforminum [Inn-Latin]
- Phenformix
- Phenoformine Hydrochloride
- Phenylethylbiguanide
- Retardo
Phenethyldiguanide Brand Names Mixture
- No information avaliable
Phenethyldiguanide Chemical_Formula
C10H15N5
Phenethyldiguanide RX_link
No information avaliable
Phenethyldiguanide fda sheet
Phenethyldiguanide msds (material safety sheet)
Phenethyldiguanide Synthesis Reference
Shapiro, Freedman, U.S. pats. 2,961,377, 3,057,780 (1960, 1962 both to U.S.V.)
Phenethyldiguanide Molecular Weight
205.26 g/mol
Phenethyldiguanide Melting Point
175-178 oC
Phenethyldiguanide H2O Solubility
210 mg/mL
Phenethyldiguanide State
Solid
Phenethyldiguanide LogP
0.759
Phenethyldiguanide Dosage Forms
No information avaliable
Phenethyldiguanide Indication
For the reatment of type II diabetes mellitus.
Phenethyldiguanide Pharmacology
Used to treat diabetes, phenformin is a biguanide (contains 2 guanidino groups) hypoglycemic agent with actions and uses similar to those of metformin (Glucophage). Both drugs work by (1) decreasing the absorption of glucose by the intestines, (2) decreasing the production of glucose in the liver, and by (3) increasing the body's ability to use insulin more effectively. More specifically, phenformin improves glycemic control by improving insulin sensitivity. Phenformin is generally considered to be associated with an unacceptably high incidence of actic acidosis. In general biguanides should be used only in stable type II diabetics who are free of liver, kidney and cardiovascular problems and who cannot be controlled with diet.
Phenethyldiguanide Absorption
No information avaliable
Phenethyldiguanide side effects and Toxicity
No information avaliable
Phenethyldiguanide Patient Information
No information avaliable
Phenethyldiguanide Organisms Affected
Humans and other mammals
