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Hydroxyzine Brand names, Hydroxyzine Analogs

Hydroxyzine Brand Names Mixture

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Hydroxyzine Chemical_Formula


Hydroxyzine RX_link


Hydroxyzine fda sheet

Hydroxyzine msds (material safety sheet)

Hydroxyzine MSDS

Hydroxyzine Synthesis Reference

Moren; U.S. Pat. 2,899,436 (1959)

Hydroxyzine Molecular Weight

374.904 g/mol

Hydroxyzine Melting Point

190 oC

Hydroxyzine H2O Solubility

< 700 mg/mL

Hydroxyzine State


Hydroxyzine LogP


Hydroxyzine Dosage Forms

Capsule; Liquid; Solution; Syrup

Hydroxyzine Indication

For symptomatic relief of anxiety and tension associated with psychoneurosis and as an adjunct in organic disease states in which anxiety is manifested. Useful in the management of pruritus due to allergic conditions such as chronic urticaria.

Hydroxyzine Pharmacology

Hydroxyzine, a piperazine antihistamine structurally related to buclizine, cyclizine, and meclizine, is used to treat histamine-mediated pruritus or pruritus due to allergy, nausea and vomiting, and, in combination with an opiate agonist, anxiolytic pain. Hydroxyzine is also used as a perioperative sedative and anxiolytic and to manage acute alcohol withdrawal. Hydroxyzine's active metabolite, cetirizine, is also used as an H1-antagonist.

Hydroxyzine Absorption

Rapidly absorbed from the gastrointestinal tract

Hydroxyzine side effects and Toxicity

Oral, rat LD50: 950 mg/kg. Symptoms of overexposure include hypersedation.

Hydroxyzine Patient Information

Hydroxyzine Organisms Affected

Humans and other mammals