Vistazine
Brand names,
Vistazine
Analogs
Vistazine
Brand Names Mixture
Vistazine
Chemical_Formula
C21H27ClN2O2
Vistazine
RX_link
http://www.rxlist.com/cgi/generic/hydrox.htm
Vistazine
fda sheet
Vistazine
msds (material safety sheet)
Vistazine
Synthesis Reference
Moren; U.S. Pat. 2,899,436 (1959)
Vistazine
Molecular Weight
374.904 g/mol
Vistazine
Melting Point
190 oC
Vistazine
H2O Solubility
< 700 mg/mL
Vistazine
State
Solid
Vistazine
LogP
3.036
Vistazine
Dosage Forms
Capsule; Liquid; Solution; Syrup
Vistazine
Indication
For symptomatic relief of anxiety and tension associated with psychoneurosis and as an adjunct in organic disease states in which anxiety is manifested. Useful in the management of pruritus due to allergic conditions such as chronic urticaria.
Vistazine
Pharmacology
Hydroxyzine, a piperazine antihistamine structurally related to buclizine, cyclizine, and meclizine, is used to treat histamine-mediated pruritus or pruritus due to allergy, nausea and vomiting, and, in combination with an opiate agonist, anxiolytic pain. Hydroxyzine is also used as a perioperative sedative and anxiolytic and to manage acute alcohol withdrawal. Hydroxyzine's active metabolite, cetirizine, is also used as an H1-antagonist.
Vistazine
Absorption
Rapidly absorbed from the gastrointestinal tract
Vistazine
side effects and Toxicity
Oral, rat LD50: 950 mg/kg. Symptoms of overexposure include hypersedation.
Vistazine
Patient Information
Vistazine
Organisms Affected
Humans and other mammals