Hy-Pam 25
Brand names,
Hy-Pam 25
Analogs
Hy-Pam 25
Brand Names Mixture
Hy-Pam 25
Chemical_Formula
C21H27ClN2O2
Hy-Pam 25
RX_link
http://www.rxlist.com/cgi/generic/hydrox.htm
Hy-Pam 25
fda sheet
Hy-Pam 25
msds (material safety sheet)
Hy-Pam 25
Synthesis Reference
Moren; U.S. Pat. 2,899,436 (1959)
Hy-Pam 25
Molecular Weight
374.904 g/mol
Hy-Pam 25
Melting Point
190 oC
Hy-Pam 25
H2O Solubility
< 700 mg/mL
Hy-Pam 25
State
Solid
Hy-Pam 25
LogP
3.036
Hy-Pam 25
Dosage Forms
Capsule; Liquid; Solution; Syrup
Hy-Pam 25
Indication
For symptomatic relief of anxiety and tension associated with psychoneurosis and as an adjunct in organic disease states in which anxiety is manifested. Useful in the management of pruritus due to allergic conditions such as chronic urticaria.
Hy-Pam 25
Pharmacology
Hydroxyzine, a piperazine antihistamine structurally related to buclizine, cyclizine, and meclizine, is used to treat histamine-mediated pruritus or pruritus due to allergy, nausea and vomiting, and, in combination with an opiate agonist, anxiolytic pain. Hydroxyzine is also used as a perioperative sedative and anxiolytic and to manage acute alcohol withdrawal. Hydroxyzine's active metabolite, cetirizine, is also used as an H1-antagonist.
Hy-Pam 25
Absorption
Rapidly absorbed from the gastrointestinal tract
Hy-Pam 25
side effects and Toxicity
Oral, rat LD50: 950 mg/kg. Symptoms of overexposure include hypersedation.
Hy-Pam 25
Patient Information
Hy-Pam 25
Organisms Affected
Humans and other mammals