Neurozina
Brand names,
Neurozina
Analogs
Neurozina
Brand Names Mixture
Neurozina
Chemical_Formula
C21H27ClN2O2
Neurozina
RX_link
http://www.rxlist.com/cgi/generic/hydrox.htm
Neurozina
fda sheet
Neurozina
msds (material safety sheet)
Neurozina
Synthesis Reference
Moren; U.S. Pat. 2,899,436 (1959)
Neurozina
Molecular Weight
374.904 g/mol
Neurozina
Melting Point
190 oC
Neurozina
H2O Solubility
< 700 mg/mL
Neurozina
State
Solid
Neurozina
LogP
3.036
Neurozina
Dosage Forms
Capsule; Liquid; Solution; Syrup
Neurozina
Indication
For symptomatic relief of anxiety and tension associated with psychoneurosis and as an adjunct in organic disease states in which anxiety is manifested. Useful in the management of pruritus due to allergic conditions such as chronic urticaria.
Neurozina
Pharmacology
Hydroxyzine, a piperazine antihistamine structurally related to buclizine, cyclizine, and meclizine, is used to treat histamine-mediated pruritus or pruritus due to allergy, nausea and vomiting, and, in combination with an opiate agonist, anxiolytic pain. Hydroxyzine is also used as a perioperative sedative and anxiolytic and to manage acute alcohol withdrawal. Hydroxyzine's active metabolite, cetirizine, is also used as an H1-antagonist.
Neurozina
Absorption
Rapidly absorbed from the gastrointestinal tract
Neurozina
side effects and Toxicity
Oral, rat LD50: 950 mg/kg. Symptoms of overexposure include hypersedation.
Neurozina
Patient Information
Neurozina
Organisms Affected
Humans and other mammals