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Placidol Brand names, Placidol Analogs

Placidol Brand Names Mixture

  • No information avaliable

Placidol Chemical_Formula

C21H27ClN2O2

Placidol RX_link

http://www.rxlist.com/cgi/generic/hydrox.htm

Placidol fda sheet

Placidol msds (material safety sheet)

Placidol MSDS

Placidol Synthesis Reference

Moren; U.S. Pat. 2,899,436 (1959)

Placidol Molecular Weight

374.904 g/mol

Placidol Melting Point

190 oC

Placidol H2O Solubility

< 700 mg/mL

Placidol State

Solid

Placidol LogP

3.036

Placidol Dosage Forms

Capsule; Liquid; Solution; Syrup

Placidol Indication

For symptomatic relief of anxiety and tension associated with psychoneurosis and as an adjunct in organic disease states in which anxiety is manifested. Useful in the management of pruritus due to allergic conditions such as chronic urticaria.

Placidol Pharmacology

Hydroxyzine, a piperazine antihistamine structurally related to buclizine, cyclizine, and meclizine, is used to treat histamine-mediated pruritus or pruritus due to allergy, nausea and vomiting, and, in combination with an opiate agonist, anxiolytic pain. Hydroxyzine is also used as a perioperative sedative and anxiolytic and to manage acute alcohol withdrawal. Hydroxyzine's active metabolite, cetirizine, is also used as an H1-antagonist.

Placidol Absorption

Rapidly absorbed from the gastrointestinal tract

Placidol side effects and Toxicity

Oral, rat LD50: 950 mg/kg. Symptoms of overexposure include hypersedation.

Placidol Patient Information

Placidol Organisms Affected

Humans and other mammals