Vistaril
Brand names,
Vistaril
Analogs
Vistaril
Brand Names Mixture
Vistaril
Chemical_Formula
C21H27ClN2O2
Vistaril
RX_link
http://www.rxlist.com/cgi/generic/hydrox.htm
Vistaril
fda sheet
Vistaril
msds (material safety sheet)
Vistaril
Synthesis Reference
Moren; U.S. Pat. 2,899,436 (1959)
Vistaril
Molecular Weight
374.904 g/mol
Vistaril
Melting Point
190 oC
Vistaril
H2O Solubility
< 700 mg/mL
Vistaril
State
Solid
Vistaril
LogP
3.036
Vistaril
Dosage Forms
Capsule; Liquid; Solution; Syrup
Vistaril
Indication
For symptomatic relief of anxiety and tension associated with psychoneurosis and as an adjunct in organic disease states in which anxiety is manifested. Useful in the management of pruritus due to allergic conditions such as chronic urticaria.
Vistaril
Pharmacology
Hydroxyzine, a piperazine antihistamine structurally related to buclizine, cyclizine, and meclizine, is used to treat histamine-mediated pruritus or pruritus due to allergy, nausea and vomiting, and, in combination with an opiate agonist, anxiolytic pain. Hydroxyzine is also used as a perioperative sedative and anxiolytic and to manage acute alcohol withdrawal. Hydroxyzine's active metabolite, cetirizine, is also used as an H1-antagonist.
Vistaril
Absorption
Rapidly absorbed from the gastrointestinal tract
Vistaril
side effects and Toxicity
Oral, rat LD50: 950 mg/kg. Symptoms of overexposure include hypersedation.
Vistaril
Patient Information
Vistaril
Organisms Affected
Humans and other mammals