Vistaril Pamoate
Brand names,
Vistaril Pamoate
Analogs
Vistaril Pamoate
Brand Names Mixture
Vistaril Pamoate
Chemical_Formula
C21H27ClN2O2
Vistaril Pamoate
RX_link
http://www.rxlist.com/cgi/generic/hydrox.htm
Vistaril Pamoate
fda sheet
Vistaril Pamoate
msds (material safety sheet)
Vistaril Pamoate
Synthesis Reference
Moren; U.S. Pat. 2,899,436 (1959)
Vistaril Pamoate
Molecular Weight
374.904 g/mol
Vistaril Pamoate
Melting Point
190 oC
Vistaril Pamoate
H2O Solubility
< 700 mg/mL
Vistaril Pamoate
State
Solid
Vistaril Pamoate
LogP
3.036
Vistaril Pamoate
Dosage Forms
Capsule; Liquid; Solution; Syrup
Vistaril Pamoate
Indication
For symptomatic relief of anxiety and tension associated with psychoneurosis and as an adjunct in organic disease states in which anxiety is manifested. Useful in the management of pruritus due to allergic conditions such as chronic urticaria.
Vistaril Pamoate
Pharmacology
Hydroxyzine, a piperazine antihistamine structurally related to buclizine, cyclizine, and meclizine, is used to treat histamine-mediated pruritus or pruritus due to allergy, nausea and vomiting, and, in combination with an opiate agonist, anxiolytic pain. Hydroxyzine is also used as a perioperative sedative and anxiolytic and to manage acute alcohol withdrawal. Hydroxyzine's active metabolite, cetirizine, is also used as an H1-antagonist.
Vistaril Pamoate
Absorption
Rapidly absorbed from the gastrointestinal tract
Vistaril Pamoate
side effects and Toxicity
Oral, rat LD50: 950 mg/kg. Symptoms of overexposure include hypersedation.
Vistaril Pamoate
Patient Information
Vistaril Pamoate
Organisms Affected
Humans and other mammals